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Merck
CN

16772

溴化氰

≥98.5% (RT)

别名:

氰化溴

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关于此项目

线性分子式:
BrCN
化学文摘社编号:
分子量:
105.92
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
208-051-2
Beilstein/REAXYS Number:
1697296
MDL number:
Assay:
≥98.5% (RT)
Form:
crystals
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InChI key

ATDGTVJJHBUTRL-UHFFFAOYSA-N

InChI

1S/CBrN/c2-1-3

SMILES string

BrC#N

vapor density

3.65 (vs air)

vapor pressure

100 mmHg ( 22.6 °C)

assay

≥98.5% (RT)

form

crystals

bp

61-62 °C (lit.)

mp

50-53 °C (lit.)

functional group

bromo

storage temp.

2-8°C

Quality Level

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Application

  • Cyanogen bromide is widely used in protein immobilization and cleavage.
  • Under von Braun reaction conditions, CNBr reacts with tertiary amines to yield respective organocyanamides.
  • It can also be used to synthesize organic intermediates like cyanuric bromide, derivatives of urea, guanidine, creatine, aryl nitriles, and a variety of heterocyclic compounds.

Other Notes

用于选择性断裂肽键(如蛋氨酸)的试剂

signalword

Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Eye Dam. 1 - Skin Corr. 1B

supp_hazards

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

>149.0 °F - closed cup

flash_point_c

> 65 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

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分析证书(COA)

Lot/Batch Number

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E. Gross
Methods in Enzymology, 11, 238-238 (1967)
Synthesis of hindered chiral guanidine bases starting from (S)-(N, N-dialkyl-aminomethyl) pyrrolidines and BrCN.
Kohn U, et al.
Tetrahedron Asymmetry, 17(5), 811-818 (2006)
von Braun reaction.
Name Reactions, 562-563 (2009)
The von Braun Reaction Applied to Azetidines.
Wright K, et al.
European Journal of Organic Chemistry, 2017(47), 195-7201 (2017)
Straightforward Conversion of Alcohols into Nitriles.
Tarrade-Matha A, et al.
Synthetic Communications, 40(11), 1646-1649 (2010)

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