169102
正二十二醇
98%
别名:
山嵛醇
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线性分子式:
CH3(CH2)21OH
化学文摘社编号:
分子量:
326.60
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
211-546-6
Beilstein/REAXYS Number:
1770470
MDL number:
Assay:
98%
InChI key
NOPFSRXAKWQILS-UHFFFAOYSA-N
InChI
1S/C22H46O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23/h23H,2-22H2,1H3
SMILES string
CCCCCCCCCCCCCCCCCCCCCCO
assay
98%
bp
180 °C/0.22 mmHg (lit.)
mp
65-72 °C (lit.)
functional group
hydroxyl
Quality Level
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General description
1-二十二烷醇可在体外抑制特定病毒（单纯疱疹病毒和呼吸道合胞病毒）在原代靶细胞内的复制。它已从短尾铁线莲中被分离。
Application
1-二十二烷醇已用于合成具有亲水性脂肪族聚醚型树枝状核和疏水性二十二烷基外周的两亲性树枝状大分子。
存储类别
11 - Combustible Solids
wgk
nwg
flash_point_f
410.0 °F
flash_point_c
210 °C
ppe
Eyeshields, Gloves, type N95 (US)
Antiviral activity of 1-docosanol, an inhibitor of lipid-enveloped viruses including herpes simplex.
D H Katz et al.
Proceedings of the National Academy of Sciences of the United States of America, 88(23), 10825-10829 (1991-12-01)
This article reports that 1-docosanol, a 22-carbon-long saturated alcohol, exerts a substantial inhibitory effect on replication of certain viruses (e.g., herpes simplex virus and respiratory syncytial virus) within primary target cells in vitro. To study the basis for its viral
Synthesis and self-assembly of amphiphilic dendrimers based on aliphatic polyether-type dendritic cores.
Cho B-K, et al.
Macromolecules, 37(11), 4227-4234 (2004)
Guadalupe Iglesias et al.
Regulatory toxicology and pharmacology : RTP, 36(1), 80-85 (2002-10-18)
Behenyl alcohol is a saturated 22-carbon, long-chain aliphatic alcohol, which has potential for use in foods as an oil-structuring and -solidifying agent in fats. Previously completed studies with behenyl alcohol indicated an absence of mutagenic or genotoxic potential. In addition
Diogo C Morelli et al.
Journal of chromatography. A, 1626, 461377-461377 (2020-08-17)
This study reports the use ofa natural deep eutectic solvent (NADES) with hollow fiber-microporous membrane liquid-liquid microextraction (HF-MMLLE) for the multiclass determination of 11 compounds classified as emerging contaminantsin water. Different deep eutectic solvents were synthetized and Thymol: Camphor (1:1
John F Marcelletti
Antiviral research, 56(2), 153-166 (2002-10-09)
Interactions between docosanol (n-docosanol, behenyl alcohol) and nucleoside or pyrophosphate analogs were investigated in vitro. The anti-HSV activity of acyclovir (ACV) was synergistically enhanced by treatment of cells with docosanol as judged by inhibition of progeny virus production and plaque
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