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线性分子式:
CH3(CH2)21OH
化学文摘社编号:
分子量:
326.60
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
211-546-6
Beilstein/REAXYS Number:
1770470
MDL number:
Assay:
98%
InChI key
NOPFSRXAKWQILS-UHFFFAOYSA-N
InChI
1S/C22H46O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23/h23H,2-22H2,1H3
SMILES string
CCCCCCCCCCCCCCCCCCCCCCO
assay
98%
bp
180 °C/0.22 mmHg (lit.)
mp
65-72 °C (lit.)
functional group
hydroxyl
Quality Level
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Application
1-二十二烷醇已用于合成具有亲水性脂肪族聚醚型树枝状核和疏水性二十二烷基外周的两亲性树枝状大分子。
General description
1-二十二烷醇可在体外抑制特定病毒(单纯疱疹病毒和呼吸道合胞病毒)在原代靶细胞内的复制。它已从短尾铁线莲中被分离。
存储类别
11 - Combustible Solids
wgk
nwg
flash_point_f
410.0 °F
flash_point_c
210 °C
ppe
Eyeshields, Gloves, type N95 (US)
Antiviral activity of 1-docosanol, an inhibitor of lipid-enveloped viruses including herpes simplex.
D H Katz et al.
Proceedings of the National Academy of Sciences of the United States of America, 88(23), 10825-10829 (1991-12-01)
This article reports that 1-docosanol, a 22-carbon-long saturated alcohol, exerts a substantial inhibitory effect on replication of certain viruses (e.g., herpes simplex virus and respiratory syncytial virus) within primary target cells in vitro. To study the basis for its viral
Synthesis and self-assembly of amphiphilic dendrimers based on aliphatic polyether-type dendritic cores.
Cho B-K, et al.
Macromolecules, 37(11), 4227-4234 (2004)
Guadalupe Iglesias et al.
Regulatory toxicology and pharmacology : RTP, 36(1), 69-79 (2002-10-18)
The genotoxic potential of behenyl alcohol, a saturated long-chain (C22:0) fatty alcohol, was examined in the Ames Salmonella typhimurium reverse mutation assay, the gene mutation, and chromosome aberrations assays in Chinese hamster V79 cells, and the micronucleus assay in NMRI
Marcin Broniatowski et al.
The journal of physical chemistry. B, 110(7), 3078-3087 (2006-02-24)
This work presents the results of phase behavior studies of two-dimensional (2D) binary systems involving semifluorinated alkanes (SFAs) and fatty alcohols. Four different SFAs were selected for investigations: (i) with a short and branched perfluorinated moiety (iF3H20), (ii) with a
John J Docherty et al.
Antiviral research, 61(1), 19-26 (2003-12-13)
Resveratrol (3,5,4'-trihydroxystilbene) is a natural component of certain foods, such as grapes, that has been shown to have anti-herpes simplex virus (HSV) activity in vitro. To determine if it is active in vivo, the abraded epidermis of SKH1 mice were
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