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175277

2H-1,4-苯并噻嗪-3(4H)-酮

Name: 2<I>H</I>-1,4-苯并噻嗪-3(4<I>H</I>)-酮
Brand: ALDRICH

97%

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关于此项目

经验公式（希尔记法）:

C₈H₇NOS

化学文摘社编号:

5325-20-2

分子量:

165.21

NACRES:

NA.22

PubChem Substance ID:

24850495

UNSPSC Code:

12352100

EC Number:

226-197-5

MDL number:

MFCD00006698

Assay:

97%

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属性

Quality Level

100

assay

97%

mp

176-178 °C (lit.)

functional group

thioether

SMILES string

O=C1CSc2ccccc2N1

InChI

1S/C8H7NOS/c10-8-5-11-7-4-2-1-3-6(7)9-8/h1-4H,5H2,(H,9,10)

InChI key

GTFMIJNXNMDHAB-UHFFFAOYSA-N

说明

General description

2H-1,4-Benzothiazin-3(4H)-one derivatives were synthesized and tested for calcium antagonistic and calmodulin antagonistic activities.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Synthesis and biological activities of new 1,4-benzothiazine derivatives.

M Kajino et al.

Chemical & pharmaceutical bulletin, 39(11), 2888-2895 (1991-11-01)

New 2H-1,4-benzothiazin-3(4H)-one derivatives possessing (4-phenyl-1-piperazinyl)alkyl moieties at the 2-position were synthesized and tested for calcium antagonistic and calmodulin antagonistic activities. Antihypertensive effects in spontaneously hypertensive rats were also evaluated. In general, these compounds were rather weak calcium channel blockers, although

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货号	GTIN
175277-25G	04061833544815