177466
4-甲基环己胺，顺反异构体混合物
97%
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关于此项目
线性分子式:
CH3C6H10NH2
化学文摘社编号:
分子量:
113.20
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
228-673-8
MDL number:
Assay:
97%
Form:
liquid
产品名称
4-甲基环己胺，顺反异构体混合物, 97%
InChI key
KSMVBYPXNKCPAJ-UHFFFAOYSA-N
InChI
1S/C7H15N/c1-6-2-4-7(8)5-3-6/h6-7H,2-5,8H2,1H3
SMILES string
CC1CCC(N)CC1
assay
97%
form
liquid
refractive index
n20/D 1.4531 (lit.)
bp
151-154 °C (lit.)
density
0.855 g/mL at 25 °C (lit.)
Quality Level
General description
Trans-4-methylcyclohexylamine is a spermidine synthase inhibitor.
signalword
Danger
hcodes
Hazard Classifications
Flam. Liq. 3 - Skin Corr. 1B
存储类别
3 - Flammable liquids
wgk
WGK 3
flash_point_f
80.6 °F - closed cup
flash_point_c
27 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
危险化学品
此项目有
Keijiro Samejima et al.
Biological & pharmaceutical bulletin, 30(10), 1943-1946 (2007-10-06)
A sensitive method for the determination of polyamines in mammalian cells was described using electrospray ionization and time-of-flight mass spectrometer. This method was 50-fold more sensitive than the previous method using ionspray ionization and quadrupole mass spectrometer. The method employed
Masaki Kobayashi et al.
Biological & pharmaceutical bulletin, 29(5), 863-867 (2006-05-03)
A close relationship between rat liver regeneration and the concentration ratio of spermidine to spermine (spd:spm) was demonstrated by the oral administration of trans-4-methylcyclohexylamine (MCHA), a specific inhibitor of putrescine aminopropyltransferase. A decrease in recovery rate of remnant liver with
Trans-4-methylcyclohexylamine, a potent new inhibitor of spermidine synthase.
A Shirahata et al.
Chemical & pharmaceutical bulletin, 36(8), 3220-3222 (1988-08-01)
Masatake Sano et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 845(1), 80-83 (2006-08-26)
An assay for spermidine synthase (SPDS) activity in rat liver has been developed using micellar electrokinetic chromatography (MEKC) with laser-induced fluorescence (LIF) detection to enable the discovery of SPDS inhibitors. The assay was established by estimating the amount of spermidine
Keijiro Samejima
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 126(8), 529-542 (2006-08-02)
This review describes my work in the field of polyamine research for the last 35 years. My research started with developing the improved synthesis of decarboxylated S-adenosylmethionine and then moved to the purification of spermidine synthase from rat prostate. I
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