180246
2-萘甲酸
98%
别名:
2-萘酸
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关于此项目
线性分子式:
C10H7CO2H
化学文摘社编号:
分子量:
172.18
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
202-217-8
Beilstein/REAXYS Number:
972039
MDL number:
Assay:
98%
Form:
powder
Quality Level
assay
98%
form
powder
mp
185-187 °C (lit.)
solubility
alcohol: soluble, diethyl ether: soluble, hot water: slightly soluble
functional group
carboxylic acid
SMILES string
OC(=O)c1ccc2ccccc2c1
InChI
1S/C11H8O2/c12-11(13)10-6-5-8-3-1-2-4-9(8)7-10/h1-7H,(H,12,13)
InChI key
UOBYKYZJUGYBDK-UHFFFAOYSA-N
General description
2-萘甲酸（NPA）是一种非竞争性N-甲基-D-天冬氨酸（NMDA）受体抑制剂。已经研究了2-萘甲酸的荧光光谱和电子吸收。
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Han Yu et al.
Molecular pharmacology, 84(4), 541-550 (2013-07-23)
N-Methyl-D-aspartate (NMDA) receptors mediate excitatory synaptic transmission in the central nervous system and play important roles in synaptic development and plasticity, but also mediate glutamate neurotoxicity. Recently, 2-naphthoic acid (NPA) and its derivatives have been identified as allosteric, noncompetitive NMDA
D P McNamara et al.
Journal of pharmaceutical sciences, 75(9), 858-868 (1986-09-01)
A mass transfer model was developed to describe the dissolution and reaction of acidic and basic compounds from a rotating disk in unbuffered water. Dissolution of two carboxylic acids, 2-naphthoic acid (1) and naproxen [(+)-6-methoxy-alpha-methyl-2-naphthaleneacetic acid, 2], and the free
K L Yu et al.
Journal of medicinal chemistry, 39(12), 2411-2421 (1996-06-07)
In search for retinoic acid receptor (RAR) selective ligands, a series of 6-substituted 2-naphthoic acid retinoids were synthesized and evaluated in vitro in a transactivation assay and a competition binding assay for all RARs. These derivatives, in general, showed RAR
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 180246-5G | 04061838754820 |
| 180246-25G | 04061838754813 |