180629
二苯基二硒醚
98%
别名:
二苯联硒
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关于此项目
线性分子式:
C6H5SeSeC6H5
化学文摘社编号:
分子量:
312.13
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
216-780-2
Beilstein/REAXYS Number:
2047179
MDL number:
Assay:
98%
assay
98%
InChI key
YWWZCHLUQSHMCL-UHFFFAOYSA-N
InChI
1S/C12H10Se2/c1-3-7-11(8-4-1)13-14-12-9-5-2-6-10-12/h1-10H
SMILES string
[Se]([Se]c1ccccc1)c2ccccc2
impurities
<2% diphenyl selenide
mp
59-61 °C (lit.)
Quality Level
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General description
二苯二硒化物是一种有机硒化合物，是苯硒醇的氧化衍生物。它是苯基硒自由基的来源。它能与多种有机亲核试剂、亲电试剂和自由基反应。
Application
二苯二硒化物的用途：在铜铁氧体纳米颗粒催化剂的存在下，通过芳基卤化物与二苯二砷化物的交叉偶联合成硒化二芳基物。
Biochem/physiol Actions
二苯基二硒化物在体内抑制脑、肝和肾脏中的δ-氨基乙酰丙酸脱水酶（δ-ALA-D）。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
危险化学品
此项目有
E N Maciel et al.
Journal of biochemical and molecular toxicology, 14(6), 310-319 (2000-11-18)
In the present study, the inhibitory effect of diphenyl diselenide and diphenyl ditelluride after in vitro, acute (a single dose), or chronic exposure (14 doses) was examined in mice 24 hours after the last administration. In vitro, diphenyl diselenide, and
Viviane Glaser et al.
Chemico-biological interactions, 206(1), 18-26 (2013-08-21)
Interest in organoselenide chemistry and biochemistry has increased in the past three decades, mainly due to their chemical and biological activities. Here, we investigated the protective effect of the organic selenium compound diphenyl diselenide (PhSe)2 (5 μmol/kg), in a mouse
César Augusto Brüning et al.
Progress in neuro-psychopharmacology & biological psychiatry, 38(2), 168-174 (2012-03-31)
Bipolar disorder (BD) is a common and severe mood disorder associated with higher rates of suicide and disability. Ouabain, a Na(+)/K(+)-ATPase inhibitor, induces behavioral changes in rats and has been used as a model of mania. The aim of this
Glaecir Roseni Mundstock Dias et al.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 30(2), 83-89 (2012-01-17)
Cognitive deficits have been observed in different animal models of adult-onset hypothyroidism. Thus, this study was delineated to evaluate whether diphenyl diselenide, an organoselenium compound with neuroprotective and antioxidant properties, could afford protection against the detrimental effects of hypothyroidism on
Juliana Trevisan da Rocha et al.
Neurobiology of learning and memory, 99, 17-24 (2012-10-23)
This study investigated the effects of co-administration of diphenyl diselenide [(PhSe)(2)] and 17β-estradiol (E(2)) on spatial reference, recognition, and working memories in ovariectomized (OVX) female mice. Sixty-day-old female adult Swiss mice were submitted to ovariectomy. From the 30th until 32nd
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