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线性分子式:
ClCOOC2H5
化学文摘社编号:
分子量:
108.52
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
208-778-5
Beilstein/REAXYS Number:
385653
MDL number:
Assay:
97%
Form:
liquid
InChI key
RIFGWPKJUGCATF-UHFFFAOYSA-N
InChI
1S/C3H5ClO2/c1-2-6-3(4)5/h2H2,1H3
SMILES string
CCOC(Cl)=O
vapor density
3.74 (vs air)
vapor pressure
3.42 psi ( 20 °C)
assay
97%
form
liquid
autoignition temp.
842 °F
refractive index
n20/D 1.395 (lit.)
bp
93 °C (lit.)
mp
−81 °C (lit.)
solubility
alcohol: miscible, benzene: miscible, chloroform: miscible, diethyl ether: miscible, water: insoluble
density
1.135 g/mL at 25 °C (lit.)
functional group
chloro
Quality Level
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Application
- 氯甲酸乙酯用于合成腈氧化物。
- 其已被用作衍生化试剂,以研究衍生化反应过程中手性非甾体类抗炎药的立体化学转化。
- 它在通过浸笔纳米光刻技术生成纳米级模板的过程中,被用于进行灵活的模板开发。
- 通过二维气相色谱法将其用作氨基酸对映体分析中的衍生化试剂。
- 它还可与氨和氰尿酰氯一起使用以将羧酸转化为腈。
Packaging
用于通过二维气相色谱对氨基酸进行对映体分析的衍生化试剂。还与氨和氰尿酰氯共同用于将羧酸转化为腈类。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Met. Corr. 1 - Skin Corr. 1B
存储类别
3 - Flammable liquids
wgk
WGK 1
flash_point_f
60.8 °F
flash_point_c
16 °C
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
监管及禁止进口产品
此项目有
M R Wright et al.
Journal of chromatography, 616(1), 59-65 (1993-06-23)
A potential problem with chiral derivatization is the possibility of stereochemical conversion during the derivatization reaction. This possibility has been examined using the non-steroidal anti-inflammatory drugs ibuprofen, ketoprofen, etodolac and flurbiprofen. To avoid possible interference from stereochemical impurities, male Sprague-Dawley
A convenient preparative method of nitrile oxides by the dehydration of primary nitro compounds with ethyl chloroformate or benzenesulfonyl chloride in the presence of triethylamine.
Shimizu T, et al.
Bulletin of the Chemical Society of Japan, 59(9), 2827-2831 (1986)
Sezin Erarpat et al.
Journal of separation science, 43(6), 1100-1106 (2019-12-21)
A green and fast analytical method for the determination of l-methionine in human plasma is presented in this study. Preconcentration of the analyte was carried out by switchable solvent liquid phase microextraction after ethyl chloroformate derivatization reaction. Instrumental detection of
Melanie Junge et al.
Chirality, 19(3), 228-234 (2007-01-19)
The chiral separation of amino acids (AA) derivatised with ethyl chloroformate by using comprehensive two-dimensional gas chromatography is reported. A commercially available enantioselective capillary column (Chirasil-l-Val) has been tested as first-dimension column. Two nonenantioselective stationary phases (BPX50 and BP1) with
Jinmao You et al.
Analytica chimica acta, 658(1), 98-105 (2010-01-20)
An improved reagent named 2-[2-(dibenzocarbazole)-ethoxy] ethyl chloroformate (DBCEC-Cl) for the determination of aliphatic amines by high-performance liquid chromatography (HPLC) with fluorescence detection and post-column online atmospheric chemical ionization-mass spectrometry (APCI-MS) identification has been developed. DBCEC-Cl could easily and quickly label
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