187305
2-(4-甲氧苯基)乙胺
≥98%
别名:
2-(4-甲氧苯基)乙胺, 4-甲氧基苯乙胺
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关于此项目
线性分子式:
CH3OC6H4CH2CH2NH2
化学文摘社编号:
分子量:
151.21
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
200-245-5
Beilstein/REAXYS Number:
508967
MDL number:
Assay:
≥98%
Form:
liquid
InChI key
LTPVSOCPYWDIFU-UHFFFAOYSA-N
InChI
1S/C9H13NO/c1-11-9-4-2-8(3-5-9)6-7-10/h2-5H,6-7,10H2,1H3
SMILES string
COc1ccc(CCN)cc1
assay
≥98%
form
liquid
Quality Level
bp
138-140 °C/20 mmHg (lit.), 254-256 °C
density
1.031 g/mL at 20 °C (lit.)
functional group
amine
General description
4-甲氧基苯乙胺抑制单胺氧化酶催化的酪胺和色胺的脱氨基作用。
4-甲氧基苯乙胺被用于通过烷基化反应合成其他有机化合物的前体。
4-甲氧基苯乙胺被用于通过烷基化反应合成其他有机化合物的前体。
Application
4-甲氧基苯乙胺用于合成以下物质：
- 吡咯并[3,2-c咔唑
- 固定硝化碱基和寡核苷酸所需的聚（4-甲氧基苯乙胺）
- 有机聚磷腈，例如聚[双（4-甲氧基苄氨基）聚磷腈和聚[双（4-甲氧基苯乙基氨基）聚磷腈]
signalword
Danger
hcodes
Hazard Classifications
Skin Corr. 1B
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
230.0 °F - closed cup
flash_point_c
110 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Synthesis and characterization of novel polyorganophosphazenes substituted with 4-methoxybenzylamine and 4-methoxyphenethylamine for in vitro release of indomethacin and 5-fluorouracil.
Gudasi KB, et al.
Reactive functional Polymers, 66(10), 1149-1157 (2006)
GC--MS analysis of N-(bromodimethoxybenzyl)-2-, 3-, and 4-methoxyphenethylamines: Inverse analogues of the psychoactive 25B-NBOMe drug
Almalki AJ, et al.
Forensic Chemistry, 21, 100277-100277 (2020)
Electrochemical Investigation of oligonucleotide-DNA hybridization on poly(4-methoxyphenethylamine).
Francielle B Silva et al.
International journal of molecular sciences, 9(7), 1173-1188 (2009-03-28)
This work describes the immobilization of purine and pyrimidine bases and immobilization/hybridization of synthetic oligonucleotides on graphite electrodes modified with poly(4-methoxyphenethylamine) produced in acid medium. The immobilization of adenine, guanine, cytosine and thymine on these modified electrodes was efficient, producing
F Peter Guengerich et al.
The Journal of biological chemistry, 277(37), 33711-33719 (2002-07-03)
Cytochrome P450 (P450) 2D6 is involved in the oxidation of a large fraction ( approximately 30%) of drugs used by humans and also catalyzes the O-demethylation of the model substrates 3- and 4-methoxyphenethylamine followed by subsequent ring hydroxylation to dopamine.
F Peter Guengerich et al.
Biochemistry, 42(5), 1245-1253 (2003-02-05)
Human cytochrome P450 (P450) 2D6 is an important enzyme involved in the metabolism of drugs, many of which are amines or contain other basic nitrogen atoms. Asp301 has generally been considered to be involved in electrostatic docking with the basic
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