188441
N,N-双(3-氨丙基)甲胺
96%
别名:
(7-氨基-4-甲基-4-氮杂庚基)胺, 1,7-二氨基-4-甲基-4-氮杂庚烷
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关于此项目
线性分子式:
CH3N(CH2CH2CH2NH2)2
化学文摘社编号:
分子量:
145.25
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
203-336-8
MDL number:
产品名称
N,N-双(3-氨丙基)甲胺, 96%
InChI key
KMBPCQSCMCEPMU-UHFFFAOYSA-N
InChI
1S/C7H19N3/c1-10(6-2-4-8)7-3-5-9/h2-9H2,1H3
SMILES string
CN(CCCN)CCCN
vapor pressure
6 mmHg ( 110 °C)
assay
96%
form
liquid
refractive index
n20/D 1.4725 (lit.)
bp
110-112 °C/6 mmHg (lit.)
density
0.901 g/mL at 25 °C (lit.)
functional group
amine
Quality Level
Application
3,3′-二氨基- N -甲基二丙胺用于合成：
- 新的双色酮衍生物，潜在的抗癌药物
- 含有二聚喹啉酮、辛诺林和邻苯二甲酰亚胺基团的多胺衍生物
- 3-（2,4-二硝基苯胺）-3'-氨基- N -甲基二丙胺
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 1 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 1
flash_point_f
217.4 °F - closed cup
flash_point_c
103 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Marta Szumilak et al.
European journal of medicinal chemistry, 45(12), 5744-5751 (2010-10-27)
The synthesis of new polyamine derivatives containing dimeric quinoline (3a-c), cinnoline (4a-c) and phthalimide (7a-c and 8a-c) moieties is described. Three different polyamines: (1,4-bis(3-aminopropyl)piperazine (a), 4,9-dioxa-1,12-dodecanediamine (b), 3,3'-diamino-N-methyldipropylamine (c) were used as linkers. The new compounds were obtained according to
Agata Szulawska-Mroczek et al.
Archiv der Pharmazie, 346(1), 34-43 (2012-10-31)
The synthesis of new bischromone derivatives (4a-c and 5a-c) as potential anticancer drugs is described. The difference in the reactivity between 4-oxo-4H-chromene-3-carboxylic acid 2 (or its methyl ester 3) and 4-oxo-4H-chromene-3-carbonyl chloride 1 with three different polyamines: 3,3'-diamino-N-methyldipropylamine (a), 1,4-bis(3-aminopropyl)piperazine
R G Anderson et al.
Proceedings of the National Academy of Sciences of the United States of America, 81(15), 4838-4842 (1984-08-01)
We report the synthesis of a probe that permits the visualization by electron microscopy of acidic organelles in intact cells. This probe, 3-(2,4-dinitroanilino)-3'-amino-N-methyldipropylamine (DAMP), is a basic congener of dinitrophenol that readily diffuses into intact cells. Its primary and tertiary
Carla Cruz et al.
PloS one, 6(11), e27078-e27078 (2011-12-02)
Useful probes of the intracellular environment that target a specific organelle in order to allow direct observation of the changes in these regions is of high current interest. Macrocyclic ligands have already revealed themselves as important selective hosts in some
Lucas Vu et al.
Theranostics, 2(12), 1160-1173 (2013-02-06)
A focused library of twenty-one cationic poly(amino ethers) was synthesized following ring-opening polymerization of two diglycidyl ethers by different oligoamines. The polymers were screened in parallel for plasmid DNA (pDNA) delivery, and transgene expression efficacies of individual polymers were compared
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