19040
(±)-1,2,4-丁三醇
technical, ≥90% (GC)
别名:
1,2,4-三羟基丁烷, 1,3,4-丁三醇, 2-脱氧赤藓糖醇, 丁基-1,2,4-三醇
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关于此项目
线性分子式:
HOCH2CH2CH(OH)CH2OH
化学文摘社编号:
分子量:
106.12
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
221-323-5
Beilstein/REAXYS Number:
1733456
MDL number:
产品名称
(±)-1,2,4-丁三醇, technical, ≥90% (GC)
InChI key
ARXKVVRQIIOZGF-UHFFFAOYSA-N
InChI
1S/C4H10O3/c5-2-1-4(7)3-6/h4-7H,1-3H2
SMILES string
OCCC(O)CO
grade
technical
assay
≥90% (GC)
refractive index
n20/D 1.473 (lit.)
n20/D 1.473
bp
190-191 °C/18 mmHg (lit.)
density
1.184 g/mL at 20 °C
1.19 g/mL at 25 °C (lit.)
functional group
hydroxyl
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Application
以1，2，4-丁三醇为起始试剂合成一系列季铵脂质。还用于合成（-）-γ-氨基-8-羟基丁酸（GABOB）、抗癫痫药和抗压药。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
370.4 °F - closed cup
flash_point_c
188 °C - closed cup
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Synthesis of cationic lipids from 1, 2, 4-butanetriol.
Ren T and Liu D.
Tetrahedron Letters, 40(2), 209-212 (1999)
L-(S)-Erythrulose: The synthesis of (R)-1, 2, 4-butanetriol and of some related C4 chirons.
Van der EE, et al.
Tetrahedron Letters, 28(40), 4759-4760 (1987)
Ramyar Azizi et al.
Journal of cellular physiology, 234(10), 19039-19047 (2019-03-30)
Recurrent pregnancy loss (RPL) is a one of the most common obstetrical complications. Since, the successful pregnancy occurs in T helper 2 (Th2)-dominant situation and since, Th1 type immunity is related to pregnancy failure, we investigated the effects of cyclosporine
Marcela B Oliveira et al.
Current drug delivery, 15(8), 1112-1122 (2018-05-08)
Bladder cancer is the second type of malignant carcinoma of the urinary tract. The treatment is time-consuming and requires maintenance doses of the drug for long period of time with important side effects. Curcumin has shown evident clinical advances in
Ming Yan et al.
Journal of molecular biology, 427(8), 1765-1778 (2014-12-21)
The SAGA (Spt-Ada-Gcn5 acetyltransferase) complex performs multiple functions in transcription activation including deubiquitinating histone H2B, which is mediated by a subcomplex called the deubiquitinating module (DUBm). The yeast DUBm comprises a catalytic subunit, Ubp8, and three additional subunits, Sgf11, Sus1
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