194557
甲氧基乙酸
98%
别名:
NSC 7300
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关于此项目
线性分子式:
CH3OCH2COOH
化学文摘社编号:
分子量:
90.08
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
210-894-6
Beilstein/REAXYS Number:
635800
MDL number:
Assay:
98%
Form:
liquid
InChI key
RMIODHQZRUFFFF-UHFFFAOYSA-N
InChI
1S/C3H6O3/c1-6-2-3(4)5/h2H2,1H3,(H,4,5)
SMILES string
COCC(O)=O
assay
98%
form
liquid
Quality Level
bp
202-204 °C (lit.)
mp
7-9 °C (lit.)
density
1.174 g/mL at 25 °C (lit.)
functional group
carboxylic acid, ether
General description
甲氧基乙酸是邻苯二甲酸酯的主要代谢物，广泛用于工业中作为胶凝剂、粘度剂和稳定剂。
Application
甲氧基乙酸被用于斑马鱼胚胎毒性试验，以评估卵内胚胎发育过程中完整脊椎动物胚胎暴露后的化学毒性。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1B - Skin Corr. 1B - STOT SE 3
target_organs
Respiratory system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 2
flash_point_f
237.2 °F - closed cup
flash_point_c
114 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Bo Yang et al.
Urology, 81(3), 696-696 (2013-01-08)
To investigate the expression pattern of Ras-related protein 1 (Rap1) during testicular development and to clarify whether its expression is developmentally regulated and whether this expression is involved in the process of germ cell apoptosis. The expression pattern of Rap1
Gargi Bagchi et al.
Reproductive biology and endocrinology : RB&E, 9, 42-42 (2011-04-02)
Optimal androgen signaling is critical for testicular development and spermatogenesis. Methoxyacetic acid (MAA), the primary active metabolite of the industrial chemical ethylene glycol monomethyl ether, disrupts spermatogenesis and causes testicular atrophy. Transcriptional trans-activation studies have indicated that MAA can enhance
Bao-Lin Li et al.
Chirality, 20(1), 35-39 (2007-10-26)
The resolutions of (9-anthryl)methoxyacetic acid (9AMAA) and (9-anthryl)hydroxyacetic acid (9AHAA) were performed by capillary electrophoresis using hydroxypropyl-beta-cyclodextrin (HP-beta-CD) as a chiral selector. Various factors affecting migration time and resolutions of these compounds were investigated with a run voltage of 20
Didik Priyandoko et al.
PloS one, 6(5), e19552-e19552 (2011-05-17)
The present day lifestyle heavily depends on industrial chemicals in the form of agriculture, cosmetics, textiles and medical products. Since the toxicity of the industrial chemicals has been a concern to human health, the need for alternative non-toxic natural products
Joshua F Robinson et al.
Toxicological sciences : an official journal of the Society of Toxicology, 118(2), 675-685 (2010-09-25)
Rat postimplantation whole-embryo culture (WEC) is a promising alternative test for the assessment of developmental toxicity. Toxicogenomic-based approaches may improve the predictive ability of the WEC model by providing a means to identify compound-specific mechanistic responses associated with embryotoxicity in
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