197173
2-肼-2-咪唑啉 氢溴酸盐
98%
别名:
2-Hydrazino-4,5-dihydroimidazole hydrobromide
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关于此项目
经验公式（希尔记法）:
C3H8N4 · HBr
化学文摘社编号:
分子量:
181.03
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
259-921-3
MDL number:
产品名称
2-肼-2-咪唑啉 氢溴酸盐, 98%
InChI key
HIJRJVVSABWXKG-UHFFFAOYSA-N
InChI
1S/C3H8N4.BrH/c4-7-3-5-1-2-6-3;/h1-2,4H2,(H2,5,6,7);1H
SMILES string
Br.NNC1=NCCN1
assay
98%
mp
185-187 °C (lit.)
Application
2-Hydrazino-2-imidazoline hydrobromide was used in synthesis of:
- some amide derivatives of 6-(4-carboxymethyloxyphenyl)-4,5-dihydro-3(2H)-pyridazinone
- 2-substituted-6-(4-acylaminophenyl)-4,5-dihydropyridazin-3(2H)-ones, potential inodilating agents
Reactant for synthesis of:
- Molecules that affect vasodilatory activity
- Sulfate-bridges dimerica copper(II) complexes
- 5-HT6 serotonin receptor antagonists
- Pd complexes
- Antidiabetic/antiobesity agents
- DNA binders
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Ranju Bansal et al.
European journal of medicinal chemistry, 44(11), 4441-4447 (2009-07-11)
Synthesis and vasodilatory activity of some amide derivatives of 6-(4-carboxymethyloxyphenyl)-4,5-dihydro-3(2H)-pyridazinone are reported. An effect of substitution at 2-position of pyridazinone ring on vasodilatory potential has also been explored. The most active compound 6-[4-(2-oxo-2-pyrrolidin-1-yl-ethoxy)phenyl]-2-(4-fluorophenyl)-4,5-dihydropyridazin-3(2H)-one (11) exhibited vasodilating activity in nanomolar range
Dinesh Kumar et al.
Acta pharmaceutica (Zagreb, Croatia), 58(4), 393-405 (2008-12-24)
The present study describes the synthesis and pharmacological evaluation of 2-substituted-6-(4-acylaminophenyl)-4,5-dihydropyridazin-3(2H)-ones as potent inodilating agents. The synthesis of target compounds 2-4 and 7-11 was achieved by Friedel-Crafts acylation of appropriate anilide derivative with succinic anhydride or methylsuccinic anhydride and subsequent
Mohamed A Hashem et al.
Carbohydrate polymers, 237, 116177-116177 (2020-04-04)
A new hydrazono-imidazoline modified cellulose (HIMC) was synthesized for selective recovery of Pt(IV), Pd(II) and Au(III) from geological samples. Cellulose was oxidized by periodate and was further functionalized with hydrazono-imidazoline moieties to afford N-donor chelating fibers. Scanning electron microscopy (SEM)
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