Merck
CN

197327

Sigma-Aldrich

S-乙酰巯基丁二酸酐

96%

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别名:
S-乙酰巯基琥珀酸酐, SAMSA
经验公式(希尔记法):
C6H6O4S
CAS号:
分子量:
174.17
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.23

质量水平

检测方案

96%

mp

83-86 °C (lit.)

储存温度

2-8°C

SMILES string

CC(=O)SC1CC(=O)OC1=O

InChI

1S/C6H6O4S/c1-3(7)11-4-2-5(8)10-6(4)9/h4H,2H2,1H3

InChI key

AHTFMWCHTGEJHA-UHFFFAOYSA-N

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一般描述

S-乙酰巯基丁二酸酐是一种胺反应性试剂,含有巯基。当被胺亲核试剂攻击时,酸酐区域打开,形成胺键。但是,在该开环反应过程中,形成了游离的羧酸根基团,使分子带负电。电荷逆转影响蛋白质的活性和分子的构象。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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M Better et al.
The Journal of biological chemistry, 267(23), 16712-16718 (1992-08-15)
A synthetic gene for the Aspergillus protein toxin mitogillin has been synthesized and expressed in Escherichia coli. The recombinant mitogillin is a potent inhibitor of protein synthesis in vitro with an IC50 of 9.7 pM. Immunoconjugates of recombinant mitogillin derivatized
Travis A Cos et al.
Journal of clinical psychology in medical settings, 27(4), 704-715 (2019-09-15)
Peer recovery specialists (PRSs) combine their personal experiences with substance use and recovery with clinical skills to support patients in treatment for or recovery from substance use. This paper provides evaluation findings from a SAMHSA-funded program that integrated a PRS
Fabio Cannone et al.
The journal of physical chemistry. B, 110(33), 16491-16498 (2006-08-18)
A fluorescein derivative (SAMSA) bound to gold nanoparticles of different diameters is investigated by time-resolved fluorescence at the single molecule level in a wide dynamic range, from nanosecond to second time scale. The significant decrease of both SAMSA excited state
Hermanson GT et al.
Bioconjugate Techniques null
Monica A Serban et al.
Biomacromolecules, 8(9), 2821-2828 (2007-08-19)
Hyaluronan (HA) derivatives containing thiol-reactive electrophilic esters were prepared to react with thiol-modified macromolecules to give cross-linker-free hydrogels. Specifically, HA was converted to two haloacetate derivatives, HA bromoacetate (HABA) and HA iodoacetate (HAIA). In cytotoxicity assays, these reactive macromolecules predictably

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