Quality Level
assay
96%
mp
83-86 °C (lit.)
storage temp.
2-8°C
SMILES string
CC(=O)SC1CC(=O)OC1=O
InChI
1S/C6H6O4S/c1-3(7)11-4-2-5(8)10-6(4)9/h4H,2H2,1H3
InChI key
AHTFMWCHTGEJHA-UHFFFAOYSA-N
General description
S-乙酰巯基丁二酸酐是一种胺反应性试剂，含有巯基。当被胺亲核试剂攻击时，酸酐区域打开，形成胺键。但是，在该开环反应过程中，形成了游离的羧酸根基团，使分子带负电。电荷逆转影响蛋白质的活性和分子的构象。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Hermanson GT et al.
Bioconjugate Techniques null
Monica A Serban et al.
Biomacromolecules, 8(9), 2821-2828 (2007-08-19)
Hyaluronan (HA) derivatives containing thiol-reactive electrophilic esters were prepared to react with thiol-modified macromolecules to give cross-linker-free hydrogels. Specifically, HA was converted to two haloacetate derivatives, HA bromoacetate (HABA) and HA iodoacetate (HAIA). In cytotoxicity assays, these reactive macromolecules predictably
M Better et al.
The Journal of biological chemistry, 267(23), 16712-16718 (1992-08-15)
A synthetic gene for the Aspergillus protein toxin mitogillin has been synthesized and expressed in Escherichia coli. The recombinant mitogillin is a potent inhibitor of protein synthesis in vitro with an IC50 of 9.7 pM. Immunoconjugates of recombinant mitogillin derivatized
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 197327-25G | 04061833013953 |
| 197327-5G | 04061833013960 |