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Merck
CN

200182

Nitrazine Yellow

indicator grade, Dye content 85 %

别名:

2-(2,4-Dinitrophenylazo)-1-hydroxynaphthalene-3,6-disulfonic acid disodium salt, 2-(2,4-Dinitrophenylazo)naphthol-3,6-disulfonic acid disodium salt, Nitrazol Yellow

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关于此项目

经验公式（希尔记法）:
C16H8N4Na2O11S2
化学文摘社编号:
5423-07-4
分子量:
542.36
NACRES:
NA.47
PubChem Substance ID:
24851961
UNSPSC Code:
12171500
EC Number:
226-549-8
MDL number:
MFCD00003938

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form

powder

InChI key

XBLIFEQTVVSTIM-QIKYXUGXSA-L

InChI

1S/C16H10N4O11S2.2Na/c21-16-11-3-2-10(32(26,27)28)5-8(11)6-14(33(29,30)31)15(16)18-17-12-4-1-9(19(22)23)7-13(12)20(24)25;;/h1-7,21H,(H,26,27,28)(H,29,30,31);;/q;2*+1/p-2/b18-17+;;

SMILES string

[Na+].[Na+].Oc1c(\N=N\c2ccc(cc2[N+]([O-])=O)[N+]([O-])=O)c(cc3cc(ccc13)S([O-])(=O)=O)S([O-])(=O)=O

grade

indicator grade

assay

>90.0% (HPLC)

composition

Dye content, 85%

solubility

H2O: 1 mg/mL

λmax

586 nm

ε (extinction coefficient)

≥35000 at 587-591 nm in 0.1 M NaOH at 0.01 g/L

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Application

Nitrazine Yellow has been used in dye-protein binding assay.

Biochem/physiol Actions

Nitrazine Yellow ( 2-(2,4-dinitrophenylazo)-1-hydroxynaphthalene-3,6-disulfonic acid disodium salt) is a pH-sensitive azo dye. It changes color from yellow to blue in pH range 6.0–7.0 and is widely used in microscopy. Throat swab immersed in nitrazine yellow is used to identify pH variations in the vagina before and after amniotomy.

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCD1402
MKBQ6886V
MKBG8083V
MKBD9527V
36296KJ

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Lien Van der Schueren et al.
Carbohydrate polymers, 91(1), 284-293 (2012-10-10)
Nanofibres functionalised with pH-sensitive dyes could greatly contribute to the development of stimuli-responsive materials. However, the application of biocompatible polymers is vital to allow for their use in (bio)medical applications. Therefore, this paper focuses on the development and characterisation of
Why certain dyes are useful for localizing the sentinel lymph node.
Tsopelas C and Sutton R
Journal of Nuclear Medicine, 43, 1377-1382 (2002)
Ibrahim A Abdelazim
Archives of gynecology and obstetrics, 287(2), 205-210 (2012-09-13)
This study was designed to detect the accuracy of the fetal fibronectin (Quick Check fFN test(®)) in diagnosing premature rupture of fetal membranes. This comparative prospective study was carried out over 1 year in Ahmadi Kuwait Oil Company (KOC) Hospital
P Ronnander et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 125, 54-63 (2018-09-18)
A mathematical model was developed to predict the transport of sumatriptan molecules across the skin followed by absorption into the bloodstream. The drug was encapsulated in dissolving polyvinylpyrrolidone-based microneedles shaped in the form of pyramids. Mass balance equations were derived
Shephali Tagore et al.
Journal of perinatal medicine, 38(6), 609-612 (2010-08-17)
to compare insulin-like growth factor binding protein-1 (IGFBP-1) (non-phosphorylated), placental alpha-microglobulin-1 (PAMG-1) and nitrazine test to diagnose premature rupture of membrane to allow gestation-specific management. we recruited 100 women with signs or symptoms of premature rupture of membranes (PROM), between
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