201626
荧光胺，异构体 I
别名:
5-氨基荧光素
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关于此项目
经验公式（希尔记法）:
C20H13NO5
化学文摘社编号:
分子量:
347.32
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
EC Number:
222-043-6
Beilstein/REAXYS Number:
48395
MDL number:
InChI key
GZAJOEGTZDUSKS-UHFFFAOYSA-N
InChI
1S/C20H13NO5/c21-10-1-4-14-13(7-10)19(24)26-20(14)15-5-2-11(22)8-17(15)25-18-9-12(23)3-6-16(18)20/h1-9,22-23H,21H2
SMILES string
Nc1ccc2c(c1)C(=O)OC23c4ccc(O)cc4Oc5cc(O)ccc35
form
powder
mp
223 °C (dec.) (lit.)
solubility
methanol: 5 mg/mL
λmax
490-501 nm
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
Quality Level
General description
荧光胺，异构体I属于衍生荧光素类。
Application
荧光胺，异构体 I 适用于特异性、灵敏的亚硝酸盐分光光度测定法。它已被用于通过竞争性羧基-胺偶联反应进行纳米颗粒的荧光标记，以显示纳米颗粒的内部情况。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
B L Allman et al.
Clinical chemistry, 27(7), 1176-1179 (1981-07-01)
We describe a fluoroimmunoassay for progesterone in serum or plasma. The assay involves use of an antiserum to progesterone-11-hemisuccinate and a labeled antigen prepared by linking fluoresceinamine to progesterone-3-carboxymethyloxime by use of a mixed-anhydride procedure. Serum or plasma samples are
A synthetic membrane-anchored antigen efficiently promotes uptake of antifluorescein antibodies and associated protein a by mammalian cells.
S L Hussey et al.
Journal of the American Chemical Society, 123(50), 12712-12713 (2001-12-14)
pH sensor based on immobilized fluoresceinamine
Saari L A
Analytical Chemistry, 54, 821-823 (1982)
D M Kranz et al.
The Journal of biological chemistry, 257(12), 6987-6995 (1982-06-25)
Binding of fluorescyl ligand by five IgG anti-fluorescyl hybridoma proteins (4-4-20, 6-10-6, 20-4-4, 20-19-=1, 20-20-3) was examined. Relative reduction in fluorescence of bound fluorescein, deuterium oxide (D2O)-induced enhancement of fluorescence, and the effects of pH on binding kinetics were measured
P Gribbon et al.
Biophysical journal, 77(4), 2210-2216 (1999-10-08)
Hyaluronan (HA) is a highly hydrated polyanion, which is a network-forming and space-filling component in the extracellular matrix of animal tissues. Confocal fluorescence recovery after photobleaching (confocal-FRAP) was used to investigate intramolecular hydrogen bonding and electrostatic interactions in hyaluronan solutions.
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