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Merck
CN

202371

Sigma-Aldrich

聚(乙二醇)

average Mn 300, hydroxyl

别名:

PEG

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About This Item

线性分子式:
H(OCH2CH2)nOH
CAS号:
MDL编号:
UNSPSC代码:
12352104
PubChem化学物质编号:
NACRES:
NA.23

product name

聚(乙二醇), average Mn 300

形式

viscous liquid

质量水平

分子量

Mn 285-315
average Mn 300

折射率

n20/D 1.463

pH值(酸碱度)

6-7 (23 °C, at 10 g/l)

粘度

5.8 cSt(210 °F)(lit.)

mp

−15-−8 °C (lit.)

密度

1.125 g/mL at 25 °C

Mw/Mn

1.1 (typical)

Ω端

hydroxyl

α端

hydroxyl

SMILES字符串

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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一般描述

聚乙二醇(PEG)是一种亲水性的聚合物。它可以通过环氧乙烷的阴离子开环聚合而被轻易的合成为不同的分子量和并带有各种端基。当交联成网络时,PEG可具有高的含水量,形成“水凝胶”。水凝胶的形成可通过电离辐射交联PEG或通过PEG大分子单体与反应性链端的共价交联而引发。PEG引其不会触发免疫反应而成为一种适合于生物学应用的材料。

应用


  • PEG modification increases thermostability and inhibitor resistance of Bst DNA polymerase.: This study demonstrates that polyethylene glycol (PEG) modification significantly enhances the thermostability and inhibitor resistance of Bst DNA polymerase, highlighting PEG′s potential in improving enzyme performance for biotechnological applications (Yang et al., 2024).

  • Development of Lyophilized Eukaryotic Cell-Free Protein Expression System Based on Leishmania tarentolae.: The incorporation of PEG in the lyophilization process of a cell-free protein expression system demonstrates its role in enhancing the stability and efficiency of biotechnological workflows (Alfaro-Palma et al., 2024).

  • A comprehensive review on singlet oxygen generation in nanomaterials and conjugated polymers for photodynamic therapy in the treatment of cancer.: This review highlights the application of PEGylated nanomaterials in photodynamic therapy, emphasizing its significance in improving biocompatibility and therapeutic efficacy in cancer treatments (Singh et al., 2024).


储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

428.0 °F - closed cup

闪点(°C)

220.00 °C - closed cup

个人防护装备

Eyeshields, Gloves


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Plasticizing collagen hydrolysate with glycerol and low-molecular weight poly(ethylene glycols)
Langmaier F, et al.
Thermochimica Acta, 469(1-2), 52-58 (2008)
Developing perylene diimide based acceptor polymers for organic photovoltaics
Liang Z, et al.
Synthetic Metals, 161(11-12), 1014-1021 (2011)
Yaqi Li et al.
Carcinogenesis, 41(7), 993-1004 (2019-11-20)
Colon signet-ring cell carcinoma (SRCC) is a rare type of malignant dedifferentiated adenocarcinomas, and is associated with poor survival. However, an in-depth study of the biological features of SRCC is hindered by the lack of a reliable in vitro model
Stephanie V Koebele et al.
Hormones and behavior, 126, 104854-104854 (2020-09-20)
17β-estradiol (E2)-containing hormone therapy is a safe, effective way to alleviate unwanted menopause symptoms. Preclinical research has focused upon the role of E2 in learning and memory using a surgically menopausal rodent model whereby the ovaries are removed. Given that
Anju Singh et al.
Scientific reports, 10(1), 3766-3766 (2020-03-01)
Th17 cells are critical drivers of autoimmune diseases and immunopathology. There is an unmet need to develop therapies targeting pathogenic Th17 cells for the treatment of autoimmune disorders. Here, we report that anxiolytic FGIN-1-27 inhibits differentiation and pathogenicity of Th17

商品

The present publication focuses on synthesis and characterization of nanothick, chemically grafted polymer films (polymer brushes) on various inorganic and polymeric substrates.

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