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Merck
CN

202495

聚乙二醇甲基醚

average MN 750, methoxy, hydroxyl

别名:

mPEG, 甲氧基聚乙二醇, 聚乙二醇单甲醚

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关于此项目

线性分子式:
CH3(OCH2CH2)nOH
化学文摘社编号:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23
MDL number:
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产品名称

聚乙二醇甲基醚, average Mn 750

vapor density

>1 (vs air)

vapor pressure

0.05 mmHg ( 20 °C)

form

paste, solid

mol wt

average Mn 750

refractive index

n20/D 1.459

viscosity

10.5 cSt(210 °F)(lit.)

transition temp

Tm 30 °C

density

1.094 g/mL at 25 °C

Ω-end

hydroxyl

α-end

methoxy

SMILES string

O(CCO)C

InChI

1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3

InChI key

XNWFRZJHXBZDAG-UHFFFAOYSA-N

Application

聚(乙二醇)甲基醚可用作:
  • 一种链转移剂,以通过金属开环寡聚反应合成两亲性嵌段共聚物。
  • 作为一种前体,用于制备视甲酸-聚乙二醇纳米组装体,以作为一种高效的药物给药系统
  • 制备与聚乳酸结合的双嵌段共聚物,并将其应用于组织工程和给药领域


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存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

359.6 °F - closed cup

flash_point_c

182 °C - closed cup

ppe

Eyeshields, Gloves



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分析证书(COA)

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商品

Biofouling control essential for device performance and safety; minimize accumulation of biomolecules and bioorganisms.

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.


Yiyi Yu et al.
Journal of pharmaceutical sciences, 102(3), 1054-1062 (2013-01-03)
To promote the application of methoxy poly(ethylene glycol)-cholesterol (mPEG-Chol), mPEG-Chol was used to prepare core-shell micelles encapsulating poorly water-soluble docetaxel (DTX-PM) by modified cosolvent evaporation method. Approaches to enhance DTX entrapment efficiency (EE) and minimize particle size were investigated in
Lina Du et al.
Anti-cancer drugs, 24(2), 172-180 (2012-09-20)
A functionalized poly(amidoamine) (PAMAM) nanocarrier was designed and prepared to deliver anticancer drugs. The nanocarrier is a copolymer with a core-shell structure with 3.0 G PAMAM as the core and sequentially conjugated poly(2-(N,N-diethylamino)ethyl methacrylate) (pDEA) and methoxy-poly(ethylene glycol) 2000 (mPEG)
Pengxiang Zhao et al.
Chemical communications (Cambridge, England), 49(31), 3218-3220 (2013-03-14)
"Click" chemistry now offers access to a great variety of triazoles, and the first example of a strategy to stabilize gold nanoparticles (AuNPs) with a new 1,2,3-triazole-mPEG ligand is developed here together with preliminary examples of possible applications.



全球贸易项目编号

货号GTIN
202495-250G04061838764997
202495-500G04061838765000