202533
二环氧化-1,3-丁二烯
97%
别名:
1,2,3,4-二环氧丁烷
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关于此项目
经验公式（希尔记法）:
C4H6O2
化学文摘社编号:
分子量:
86.09
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
8614599
InChI
1S/C4H6O2/c1-3(5-1)4-2-6-4/h3-4H,1-2H2
SMILES string
C1OC1C2CO2
InChI key
ZFIVKAOQEXOYFY-UHFFFAOYSA-N
vapor pressure
25 mmHg ( 56 °C)
assay
97%
form
liquid
impurities
<3% methylene chloride
refractive index
n20/D 1.434 (lit.)
bp
56-58 °C/25 mmHg (lit.)
mp
2-4 °C (lit.)
density
1.113 g/mL at 25 °C (lit.)
storage temp.
2-8°C
Quality Level
General description
1,3-二环氧丁烷是多功能有机化合物，具有二个环氧基组成的双环氧化物结构。这一特性令其在聚合反应中发挥有效的交联作用，提高产物的机械强度和热稳定性。
Application
1,3-二环氧丁烷可用于：
- 作为前体合成用于药物递送和组织工程的聚氨基醇醚微结构水凝胶。有助于提高水凝胶的机械强度和热响应能力。
- 作为胶体通过绿色合成法制备环氧-胺止血海绵用于控制出血。它可促进环氧-胺基质中的三维网络形成。
signalword
Danger
Hazard Classifications
Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Muta. 1B - Skin Corr. 1B
存储类别
3 - Flammable liquids
wgk
WGK 3
flash_point_f
114.8 °F - closed cup
flash_point_c
46 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
非剧毒-急性毒性1
此项目有
Filipa Ponte et al.
Toxicology, 289(1), 52-58 (2011-08-03)
The biotransformation and oxidative stress may contribute to 1,2:3,4-diepoxybutane (DEB)-induced toxicity to human lymphocytes of Fanconi Anemia (FA) patients. Thus, the identification of putative inhibitors of bioactivation, as well as the determination of the protective role of oxidant defenses, on
Qingjun Liu et al.
Biosensors & bioelectronics, 26(4), 1672-1678 (2010-10-15)
Olfactory systems of human beings and animals have the abilities to sense and distinguish varieties of odors. In this study, a bioelectronic nose was constructed by fixing biological tissues onto the surface of light-addressable potentiometric sensor (LAPS) to mimic human
Uthpala Seneviratne et al.
Chemical research in toxicology, 23(10), 1556-1567 (2010-09-30)
1,2,3,4-Diepoxybutane (DEB) is a carcinogenic metabolite of 1,3-butadiene (BD), an important industrial and environmental chemical present in urban air and in cigarette smoke. DEB is considered the ultimate carcinogenic species of BD because of its potent genotoxicity and mutagenicity attributed
Erin D Michaelson-Richie et al.
Journal of proteome research, 9(9), 4356-4367 (2010-07-30)
1,2,3,4-diepoxybutane (DEB) is a strongly genotoxic diepoxide hypothesized to be the ultimate carcinogenic metabolite of the common industrial chemical and environmental carcinogen 1,3-butadiene. DEB is a bis-electrophile capable of cross-linking cellular biomolecules to form DNA-DNA and DNA-protein cross-links (DPCs), which
Michelle L Webb et al.
The Journal of hand surgery, 36(6), 1052-1057 (2011-04-26)
Fanconi anemia (FA) is a rare genetic disorder of DNA repair that with near uniformity leads to bone marrow failure and resulting morbidity and mortality. Approximately 50% of FA patients are born with anomalies of the thumb or thumb and
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