205494
二丁基二氯化锡
96%
别名:
二丁基二氯锡
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关于此项目
线性分子式:
(CH3CH2CH2CH2)2SnCl2
化学文摘社编号:
分子量:
303.84
UNSPSC Code:
12352103
NACRES:
NA.22
PubChem Substance ID:
EC Number:
211-670-0
Beilstein/REAXYS Number:
3535484
MDL number:
Assay:
96%
Form:
solid
InChI key
RJGHQTVXGKYATR-UHFFFAOYSA-L
InChI
1S/2C4H9.2ClH.Sn/c2*1-3-4-2;;;/h2*1,3-4H2,2H3;2*1H;/q;;;;+2/p-2
SMILES string
CCCC[Sn](Cl)(Cl)CCCC
assay
96%
form
solid
bp
135 °C/10 mmHg (lit.)
mp
37-40 °C (lit.)
Quality Level
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Application
- 二丁基锡化合物对PPARγ/RXRα活性的影响：研究包括二氯化二丁基锡在内的各种二丁基锡化合物对哺乳动物细胞脂肪生成和炎症的影响，强调其对PPARγ/RXRα通路的影响（Milton et al., 2017）。
signalword
Danger
Hazard Classifications
Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Muta. 2 - Repr. 1B - Skin Corr. 1B - Skin Sens. 1 - STOT RE 1 Oral - STOT SE 1 Oral
target_organs
thymus
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
危险化学品
此项目有
Synthetic Communications, 12, 495-495 (1982)
Makoto Ema et al.
Environmental toxicology, 22(1), 44-52 (2007-02-14)
In this study, we examined the adverse effects of dibutyltin on initiation and maintenance of pregnancy after maternal administration during early pregnancy in mice. Following successful mating, female ICR mice were given dibutyltin dichloride (DBTCl) at 0, 7.6, 15.2, or
Fei Jiang et al.
Pancreas, 40(7), 1091-1096 (2011-09-20)
The α-tocopherol and tocotrienol-rich fraction (TRF) are considered effective antioxidants. This study aimed to compare the antioxidative and antifibrotic effects of α-tocopherol and TFR in dibutylin dichloride (DBTC)-induced chronic pancreatitis (CP) rats. Oral administration of α-tocopherol and TFR (both 800
H F Zhao et al.
Gut, 54(12), 1759-1767 (2005-11-15)
Monocyte chemoattractant protein 1 (MCP-1) is a member of the C-C chemokine family and exerts strong chemoattractant activity in monocytes, macrophages, and lymphocytes. Rat pancreatic fibrosis induced by dibutyltin dichloride (DBTC) is considered to be an appropriate chronic pancreatitis model
Marina Vardanyan et al.
Pain, 151(2), 257-265 (2010-07-06)
Pancreatic pain resulting from chronic inflammation of the pancreas is often intractable and clinically difficult to manage with available analgesics reflecting the need for more effective therapies. The mechanisms underlying pancreatitis pain are not well understood. Here, the possibility that
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