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Merck
CN

210218

3-二甲氨基-1,2-丙二醇

98%

别名:

(±)-3-(二甲氨基)-1,2-丙二醇, 1,2-二羟基-3-(二甲氨基)丙烷, 甲氧苄啶

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关于此项目

线性分子式:
(CH3)2NCH2CH(OH)CH2OH
化学文摘社编号:
分子量:
119.16
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
210-802-4
MDL number:
Assay:
98%
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Quality Level

assay

98%

refractive index

n20/D 1.4609 (lit.)

bp

216-217 °C (lit.)

density

1.004 g/mL at 25 °C (lit.)

functional group

amine, hydroxyl

SMILES string

CN(C)CC(O)CO

InChI

1S/C5H13NO2/c1-6(2)3-5(8)4-7/h5,7-8H,3-4H2,1-2H3

InChI key

QCMHUGYTOGXZIW-UHFFFAOYSA-N

Application

3-二甲胺基-1,2-丙二醇可用于制备:
  • 合成阳离子脂质,N-[1-(2,3-二油氧基)丙基-N,N,N-三甲基氯化铵(DOTMA),用于DNA转染方案
  • 茚满衍生的噁唑啉


pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

存储类别

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

221.0 °F - closed cup

flash_point_c

105 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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An efficient synthesis of indane-derived bis (oxazoline) and its application to hetero Diels-Alder reactions on polymer support.
Kurosu M, et al.
Tetrahedron Letters, 45(1), 145-148 (2004)
P L Felgner et al.
Proceedings of the National Academy of Sciences of the United States of America, 84(21), 7413-7417 (1987-11-01)
A DNA-transfection protocol has been developed that makes use of a synthetic cationic lipid, N-[1-(2,3-dioleyloxy)propyl]-N,N,N-trimethylammonium chloride (DOTMA). Small unilamellar liposomes containing DOTMA interact spontaneously with DNA to form lipid-DNA complexes with 100% entrapment of the DNA, DOTMA facilitates fusion of
Shuo Fang et al.
International journal of pharmaceutics, 493(1-2), 460-465 (2015-08-11)
A novel dual drug-tailed betaine conjugate amphiphile has been firstly synthesized in which the polar headgroup is derived from glycine betaine and the hydrophobic tails are chlorambucil molecules. The newly prepared conjugate undergoes self-assembly to form stable liposome-like nanocapsules as



全球贸易项目编号

货号GTIN
210218-25ML04061838771179