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Merck
CN

211281

Sigma-Aldrich

9-菲酚

technical grade

别名:

9-羟基菲

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关于此项目

经验公式(希尔记法):
C14H10O
CAS Number:
分子量:
194.23
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
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等级

technical grade

质量水平

mp

139-143 °C (lit.)

SMILES字符串

Oc1cc2ccccc2c3ccccc13

InChI

1S/C14H10O/c15-14-9-10-5-1-2-6-11(10)12-7-3-4-8-13(12)14/h1-9,15H

InChI key

DZKIUEHLEXLYKM-UHFFFAOYSA-N

应用

9-菲咯尔被用来研究单壁碳纳米管的 ck-edge 和 ok-edge 近边 X 射线吸收精细结构 (NEXAFS) 光谱

生化/生理作用

9-邻菲罗是瞬时受体电位美拉斯汀 4 (TRPM) 通道的抑制剂,TRPM 通道是一种 Ca2+ 激活的非选择性阳离子通道

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Stefano Masoli et al.
Communications biology, 3(1), 222-222 (2020-05-10)
The cerebellar granule cells (GrCs) are classically described as a homogeneous neuronal population discharging regularly without adaptation. We show that GrCs in fact generate diverse response patterns to current injection and synaptic activation, ranging from adaptation to acceleration of firing.
Amy C Smith et al.
American journal of physiology. Cell physiology, 304(5), C467-C477 (2013-01-11)
Members of the transient receptor potential (TRP) channel superfamily, including the Ca(2+)-activated monovalent cation-selective TRP melastatin 4 (TRPM4) channel, have been recently identified in the urinary bladder. However, their expression and function at the level of detrusor smooth muscle (DSM)
Te-Ling Lu et al.
Biomolecules, 10(2) (2020-01-30)
: GAL-021 has recently been developed as a novel breathing control modulator. However, modifications of ionic currents produced by this agent remain uncertain, although its efficacy in suppressing the activity of big-conductance Ca2+-activated K+ (BKCa) channels has been reported. In
Ana Mrejeru et al.
The Journal of physiology, 589(Pt 10), 2497-2514 (2011-04-14)
Nigral dopamine neurons are transiently activated by high frequency glutamatergic inputs relaying reward-predicting sensory information. The tonic firing pattern of dopamine cells responds to these inputs with a transient burst of spikes that requires NMDA receptors. Here, we show that
T Grand et al.
British journal of pharmacology, 153(8), 1697-1705 (2008-02-26)
TRPM4 and TRPM5 are calcium-activated non-selective cation channels with almost identical characteristics. TRPM4 is detected in several tissues including heart, kidney, brainstem, cerebral artery and immune system whereas TRPM5 expression is more restricted. Determination of their roles in physiological processes

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