218707
环磷酰胺 一水合物
≥98%
别名:
2-[双(2-氯乙基)氨基]四氢-2H-1,3,2-噁磷-2-氧化物, Cytoxan
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经验公式（希尔记法）:
C7H15Cl2N2O2P · H2O
化学文摘社编号:
分子量:
279.10
EC Number:
200-015-4
UNSPSC Code:
12352103
MDL number:
Beilstein/REAXYS Number:
4678992
InChI
1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2
InChI key
PWOQRKCAHTVFLB-UHFFFAOYSA-N
SMILES string
[H]O[H].ClCCN(CCCl)P1(=O)NCCCO1
assay
≥98%
mp
49-51 °C (lit.)
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Biochem/physiol Actions
广泛用于癌症化疗的细胞毒性氮芥衍生物。它可与 DNA 交联、导致链断裂并诱导突变。
环磷酰胺是一种广泛用于癌症化疗的具有细胞毒性的氮芥衍生物。它可与 DNA 交联、导致链断裂并诱导突变。其临床活性与乙醛脱氢酶 1 (ALDH1) 的活性降低相关。
Features and Benefits
癌症研究工具。
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