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Merck
CN

219827

Sigma-Aldrich

L-α-羟基异己酸

98%

别名:

2-羟基-4-甲基戊酸, L-2-羟基-4-甲基戊酸, L-白氨酸

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关于此项目

线性分子式:
(CH3)2CHCH2CH(OH)CO2H
CAS Number:
分子量:
132.16
EC 号:
MDL编号:
UNSPSC代码:
51113400
PubChem化学物质编号:
NACRES:
NA.22
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质量水平

方案

98%

表单

powder

旋光性

[α]22/D −26.3°, c = 1 in 1 M NaOH

mp

78-80 °C (lit.)

官能团

carboxylic acid
hydroxyl

SMILES字符串

CC(C)C[C@H](O)C(O)=O

InChI

1S/C6H12O3/c1-4(2)3-5(7)6(8)9/h4-5,7H,3H2,1-2H3,(H,8,9)/t5-/m0/s1

InChI key

LVRFTAZAXQPQHI-YFKPBYRVSA-N

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

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Antti A Mero et al.
Journal of the International Society of Sports Nutrition, 7, 1-1 (2010-01-07)
Alfa-Hydroxy-isocaproic acid (HICA) is an end product of leucine metabolism in human tissues such as muscle and connective tissue. According to the clinical and experimental studies, HICA can be considered as an anti-catabolic substance. The present study investigated the effects
Charles H Lang et al.
American journal of physiology. Endocrinology and metabolism, 305(3), E416-E428 (2013-06-13)
Muscle disuse atrophy is observed routinely in patients recovering from traumatic injury and can be either generalized resulting from extended bed rest or localized resulting from single-limb immobilization. The present study addressed the hypothesis that a diet containing 5% α-hydroxyisocaproic
Fernanda U Fontella et al.
Metabolic brain disease, 17(1), 47-54 (2002-03-16)
In this study we investigated the in vitro effects of the metabolites accumulating in maple syrup urine disease on lipid peroxidation in brain of young rats. Chemiluminescence and thiobarbituric acid-reactive substances were measured in brain homogenates from 7- and 30-day-old
Takayoshi Awakawa et al.
Nature communications, 9(1), 3534-3534 (2018-09-01)
Reprogramming of the NRPS/PKS assembly line is an attractive method for the production of new bioactive molecules. However, it is usually hampered by the loss of intimate domain/module interactions required for the precise control of chain transfer and elongation reactions.
K D Webster et al.
Archives of biochemistry and biophysics, 273(2), 562-571 (1989-09-01)
L-Thiomorpholine-3-carboxylic acid (L-TMC) is a cyclized analog of S-(2-chloroethyl)-L-cysteine, which is cytotoxic in vitro and nephrotoxic in vivo. To determine whether L-TMC may play a role in S-(2-chloroethyl)-L-cysteine-induced toxicity, the cytotoxicity of L-TMC was studied in isolated rat kidney cells.

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