219991
4-咪唑乙酸 盐酸盐
98%
别名:
(4-咪唑基)乙酸 盐酸盐, I4AA
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关于此项目
经验公式（希尔记法）:
C5H6N2O2 · HCl
化学文摘社编号:
分子量:
162.57
UNSPSC Code:
12352005
NACRES:
NA.22
PubChem Substance ID:
EC Number:
221-840-6
Beilstein/REAXYS Number:
3701591
MDL number:
Assay:
98%
Form:
solid
InChI key
MWHLCFYPFGFBQO-UHFFFAOYSA-N
InChI
1S/C5H6N2O2.ClH/c8-5(9)1-4-2-6-3-7-4;/h2-3H,1H2,(H,6,7)(H,8,9);1H
SMILES string
Cl.OC(=O)Cc1c[nH]cn1
assay
98%
form
solid
Quality Level
solubility
water: soluble 100 mg/mL, clear, faintly yellow
functional group
carboxylic acid
Application
在以下合成中使用了 4-咪唑乙酸盐酸盐：
- 咪唑基-聚乙烯亚胺改性纳米颗粒
- 潜在金属离子螯合剂吡啶基和咪唑基功能化碳蛋白
Biochem/physiol Actions
GABAC 受体上的竞争性拮抗剂。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Archana Swami et al.
International journal of pharmaceutics, 335(1-2), 180-192 (2006-12-16)
The derivatives of polyethylenimine (PEI 25 and 750kDa) were synthesized by partially substituting their amino groups with imidazolyl moieties. The series of imidazolyl-PEIs thus obtained were cross-linked with polyethylene glycol (PEG) to get imidazolyl-PEI-PEG nanoparticles (IPP). The component of hydrophobicity
A Pernille Tofteng et al.
Organic & biomolecular chemistry, 5(14), 2225-2233 (2007-07-05)
De novo design and total chemical synthesis of proteins provides a powerful approach for biological and biophysical studies with the ability to prepare artificial proteins with tailored properties, potentially of importance for biophysical studies, material science, nanobioscience, and as molecular
Karin N Barnouin et al.
Proteomics, 5(17), 4376-4388 (2005-11-19)
IMAC can be used to selectively enrich phosphopeptides from complex peptide mixtures, but co-retention of acidic peptides together with the failure to retain some phosphopeptides restricts the general utility of the method. In this study Fe(III)-IMAC was qualitatively and quantitatively
Nan Yan et al.
Small (Weinheim an der Bergstrasse, Germany), 15(41), e1903016-e1903016 (2019-08-20)
Developing tumor-responsive diagnosis and therapy strategies for tumor theranostics is still a challenge owing to their high accuracy and specificity. Herein, an AND logic gated-DNA nanodevice, based on the fluorescence nucleic acid probe and polymer-modified MnO2 nanosheets, for glutathione (GSH)-gated
A Kammeyer et al.
Biochimica et biophysica acta, 1526(3), 277-285 (2001-06-19)
cis-Urocanic acid (cis-UCA), formed from trans-urocanic acid (trans-UCA) by photoisomerization, has been shown to mimic suppressive effects of UV on the immune system. It is our hypothesis that UCA oxidation products in the skin play a role in the process
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