219991
4-咪唑乙酸 盐酸盐
98%
别名:
(4-咪唑基)乙酸 盐酸盐, I4AA
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关于此项目
经验公式（希尔记法）:
C5H6N2O2 · HCl
化学文摘社编号:
分子量:
162.57
UNSPSC Code:
12352005
NACRES:
NA.22
PubChem Substance ID:
EC Number:
221-840-6
Beilstein/REAXYS Number:
3701591
MDL number:
产品名称
4-咪唑乙酸 盐酸盐, 98%
InChI key
MWHLCFYPFGFBQO-UHFFFAOYSA-N
InChI
1S/C5H6N2O2.ClH/c8-5(9)1-4-2-6-3-7-4;/h2-3H,1H2,(H,6,7)(H,8,9);1H
SMILES string
Cl.OC(=O)Cc1c[nH]cn1
assay
98%
form
solid
mp
218-222 °C (lit.)
solubility
water: soluble 100 mg/mL, clear, faintly yellow
functional group
carboxylic acid
Quality Level
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Application
在以下合成中使用了 4-咪唑乙酸盐酸盐：
- 咪唑基-聚乙烯亚胺改性纳米颗粒
- 潜在金属离子螯合剂吡啶基和咪唑基功能化碳蛋白
Biochem/physiol Actions
GABAC 受体上的竞争性拮抗剂。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
A Pernille Tofteng et al.
Organic & biomolecular chemistry, 5(14), 2225-2233 (2007-07-05)
De novo design and total chemical synthesis of proteins provides a powerful approach for biological and biophysical studies with the ability to prepare artificial proteins with tailored properties, potentially of importance for biophysical studies, material science, nanobioscience, and as molecular
Nan Yan et al.
Small (Weinheim an der Bergstrasse, Germany), 15(41), e1903016-e1903016 (2019-08-20)
Developing tumor-responsive diagnosis and therapy strategies for tumor theranostics is still a challenge owing to their high accuracy and specificity. Herein, an AND logic gated-DNA nanodevice, based on the fluorescence nucleic acid probe and polymer-modified MnO2 nanosheets, for glutathione (GSH)-gated
Archana Swami et al.
International journal of pharmaceutics, 335(1-2), 180-192 (2006-12-16)
The derivatives of polyethylenimine (PEI 25 and 750kDa) were synthesized by partially substituting their amino groups with imidazolyl moieties. The series of imidazolyl-PEIs thus obtained were cross-linked with polyethylene glycol (PEG) to get imidazolyl-PEI-PEG nanoparticles (IPP). The component of hydrophobicity
Xumin Zhang et al.
Molecular & cellular proteomics : MCP, 6(11), 2032-2042 (2007-08-07)
A new method for enrichment of phosphopeptides in complex mixtures derived by proteolytic digestion of biological samples has been developed. The method is based on calcium phosphate precipitation of the phosphopeptides prior to further enrichment with established affinity enrichment methods.
Greg T Cantin et al.
Analytical chemistry, 79(12), 4666-4673 (2007-05-26)
An automated online multidimensional liquid chromatography system coupled to ESI-based tandem mass spectrometry was used to assess the effectiveness of TiO2 in the enrichment of phosphopeptides from tryptic digests of protein mixtures. By monitoring the enrichment of phosphopeptides, an optimized
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