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经验公式(希尔记法):
C22H24BrO2P
化学文摘社编号:
分子量:
431.30
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352107
EC Number:
257-977-3
MDL number:
Assay:
98%
Form:
powder
InChI key
FRHRVQQUICVJDG-UHFFFAOYSA-M
InChI
1S/C22H22O2P.BrH/c1-4-10-19(11-5-1)25(18-22-23-16-17-24-22,20-12-6-2-7-13-20)21-14-8-3-9-15-21;/h1-15,22H,16-18H2;1H/q+1;/p-1
SMILES string
[Br-].C1COC(C[P+](c2ccccc2)(c3ccccc3)c4ccccc4)O1
assay
98%
form
powder
reaction suitability
reaction type: C-C Bond Formation
mp
193-195 °C (lit.)
functional group
ether, phosphine
Application
Reactant for:
- Preparation of a ratiometric fluorescent probe for specific detection of cysteine over homocysteine and glutathione
- Microwave-assisted synthesis of KN-93 as inhibitor of calmodulin kinase II
- Preparation of fluorinated spirobenzofuran piperidines as s1 receptor ligands
- Synthesis and antitumor agents
- Regio-selective preparation of indole derivatives via rhodium-catalyzed domino hydroformylation/indolization
signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Ying Li et al.
Chemistry, an Asian journal, 12(16), 2098-2103 (2017-05-31)
The development of a fluorescent probe to distinguish between cysteine (Cys) and homocysteine (Hcy) is always a challenge owing to their structural similarity, and the simultaneous detection of Cys and Hcy by utilizing different emission channels is especially difficult. In
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