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Merck
CN

232904

3-氨基-2-噻吩甲酸甲酯

99%

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关于此项目

经验公式(希尔记法):
C6H7NO2S
化学文摘社编号:
分子量:
157.19
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
244-895-8
MDL number:
Assay:
99%
Form:
solid
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InChI key

TWEQNZZOOFKOER-UHFFFAOYSA-N

InChI

1S/C6H7NO2S/c1-9-6(8)5-4(7)2-3-10-5/h2-3H,7H2,1H3

SMILES string

COC(=O)c1sccc1N

assay

99%

form

solid

bp

100-102 °C/0.1 mmHg (lit.)

mp

62-64 °C (lit.)

functional group

ester

General description

在三乙胺的存在下,3-氨基-2-噻吩甲酸甲酯可与腙酰氯化物反应形成相应的N-芳基氨基腙

Application

3-氨基-2-噻吩甲酸甲酯可用于:
  • 合成4-硝基和4-氨基噻吩基尿素
  • 总合成喹唑啉酮咔啉生物碱
  • 制备噻吩嘧啶酮类似物

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Mohanta PK and Kim K.
Tetrahedron Letters, 43(22), 3993-3996 (2002)
Synthesis and Properties of Some New 1, 4-Dihydrothieno [3, 2-e][1, 2, 4] triazepin-5-ones.
Sabri SS, et al.
Zeitschrift fur Naturforschung, B: Chemical Sciences, 61(1), 65-65 (2006)
Donald L Hertzog et al.
Bioorganic & medicinal chemistry letters, 16(18), 4723-4727 (2006-07-28)
Optimization of a series of constrained melanin-concentrating hormone receptor 1 (MCH R1) antagonists has provided compounds with potent and selective MCH R1 activity. Details of the optimization process are provided and the use of one of the compounds in an
A M Redman et al.
Bioorganic & medicinal chemistry letters, 11(1), 9-12 (2001-01-05)
Inhibitors of the MAP kinase p38 are potentially useful for the treatment for osteoporosis, arthritis, and other inflammatory diseases. A series of thienyl, furyl, and pyrrolyl ureas has been identified as potent p38 inhibitors, displaying in vitro activity in the

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