246425
联甲基苯乙烯酮
98%
别名:
1,5-二苯-1,4-戊二烯-3-酮, 反,反-二亚苄基丙酮
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关于此项目
线性分子式:
C6H5CH=CHCOCH=CHC6H5
化学文摘社编号:
分子量:
234.29
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
98%
Form:
solid
Quality Level
assay
98%
form
solid
mp
104-107 °C (lit.)
solubility
acetone: soluble(lit.), alcohol: slightly soluble(lit.), chloroform: soluble(lit.), diethyl ether: slightly soluble(lit.), water: insoluble(lit.)
functional group
ketone, phenyl
SMILES string
O=C(\C=C\c1ccccc1)/C=C/c2ccccc2
InChI
1S/C17H14O/c18-17(13-11-15-7-3-1-4-8-15)14-12-16-9-5-2-6-10-16/h1-14H/b13-11+,14-12+
InChI key
WMKGGPCROCCUDY-PHEQNACWSA-N
Application
反式 -二亚苄基丙酮被用作铜催化的咪唑 N -芳基化反应的添加剂 。
涉及的反应物：
- Nazarov 样环化
- 转移氢化
- Lewis 酸介导的缩合
- 异-Diels-Alder 反应
- 不对称 1,4-加成反应
- Michael 加成反应
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Rahul Balasaheb Aher et al.
Bioorganic & medicinal chemistry letters, 21(10), 3034-3036 (2011-04-16)
A series of dibenzylideneacetones (A1-A12) and some of their pyrazolines (B1-B4) were synthesized and evaluated in vitro for blood stage antiplasmodial properties in Plasmodium falciparum culture using SYBR-green-I fluorescence assay. The compound (1E, 4E)-1,5-bis(3,4-dimethoxyphenyl)penta-1,4-dien-3-one (A9) was found to be the
Kiyomori A, et al.
Tetrahedron Letters, 40(14), 2657-2660 null
Regina Appiah-Opong et al.
European journal of medicinal chemistry, 43(8), 1621-1631 (2008-02-06)
Inhibition of cytochrome P450 (CYP) is a major cause of drug-drug interactions. In this work, inhibitory potentials of 33 curcumin analogues, i.e. 2,6-dibenzylidenecyclohexanone (A series), 2,5-dibenzylidenecyclopentanone (B series) and 1,4-pentadiene-3-one (C series) substituted analogues of curcumin towards recombinant human CYP1A2
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 246425-10G | 04061825859323 |
| 246425-50G | 04061825859606 |