251054
2-羟基吡啶-3-羧酸
98%
别名:
2-羟基烟酸, 2-羟基吡啶-3-羧酸
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关于此项目
经验公式（希尔记法）:
C6H5NO3
化学文摘社编号:
分子量:
139.11
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
210-198-2
Beilstein/REAXYS Number:
472167
MDL number:
产品名称
2-羟基吡啶-3-羧酸, 98%
InChI key
UEYQJQVBUVAELZ-UHFFFAOYSA-N
InChI
1S/C6H5NO3/c8-5-4(6(9)10)2-1-3-7-5/h1-3H,(H,7,8)(H,9,10)
SMILES string
OC(=O)c1cccnc1O
assay
98%
form
solid
mp
258-261 °C (lit.)
solubility
formic acid: soluble 50 mg/mL, clear, colorless to yellow
functional group
carboxylic acid
Quality Level
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Application
2-Hydroxypyridine-3-carboxylic acid may be used in chemical synthesis.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Anita V Thomae et al.
Pharmaceutical research, 24(8), 1457-1472 (2007-03-28)
Lipid bilayers regulate the passage of solutes into and between cellular compartments. A general prerequisite for this passage is the partitioning of the solute into the bilayer. We investigated the relationship between bilayer partitioning and permeation of three drug-like acids
Ade Arsianti et al.
Bioorganic & medicinal chemistry letters, 20(14), 4018-4020 (2010-07-14)
Novel 2-hydroxynicotinoyl-serine-butyl esters have been synthesized. Three-step reactions from L-serine by esterification with n-butanol, amidation with 2-hydroxynicotinic acid and esterification with the corresponding carboxylic acids gave AD-1, AD-2 and AD-3. The toxicity level of esters were determined by Brine shrimp
Anita V Thomae et al.
Biophysical journal, 89(3), 1802-1811 (2005-06-14)
According to the pH-partition hypothesis the charged species of organic compounds do not contribute to lipid bilayer permeation as they generally show negligible partitioning into n-octanol. With this assumption, membrane permeation is related to the molar fraction of the neutral
V B Di Marco et al.
Annali di chimica, 91(9-10), 595-603 (2002-01-05)
The formation of complexes between iron(III) and two ligands of possible relevance to chelation therapy, 2-hydroxynicotinic acid and 3-hydroxypicolinic acid, in aqueous 0.6 m (Na)Cl at 25 degrees C, has been investigated by means of potentiometric titrations and UV measurements.
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