253596
16-羟硬脂酸，自由基
别名:
2-(14-羧十四烷基)-2-乙基-4,4-二甲基-3-恶唑烷基氧自由基
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关于此项目
经验公式（希尔记法）:
C22H42NO4
化学文摘社编号:
分子量:
384.57
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352106
MDL number:
InChI
1S/C22H42NO4/c1-4-22(23(26)21(2,3)19-27-22)18-16-14-12-10-8-6-5-7-9-11-13-15-17-20(24)25/h4-19H2,1-3H3,(H,24,25)
SMILES string
CCC1(CCCCCCCCCCCCCCC(O)=O)OCC(C)(C)N1[O]
InChI key
RPAZYIOIDZRJOO-UHFFFAOYSA-N
form
solid
mp
47-55 °C (lit.)
functional group
carboxylic acid
ether
storage temp.
2-8°C
Quality Level
Application
用于膜流动性研究的自旋标记物。
用于膜研究，包括：
- 利用1H动态核极化，研究脂质双层内部水的动力学和状态
- 脂肪酸的分布
- 氮氧化物的横向弛豫，用于PELDOR光谱学分析
- 不同脂质成分对抗去垢剂膜的影响
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
Eyeshields, Gloves, type N95 (US)
N Rapoport et al.
Archives of biochemistry and biophysics, 384(1), 100-108 (2001-01-09)
To assess the effect of a polymeric surfactant, Pluronic P-105 on the activity of electron transport chains in the mitochondria of HL-60 cells, the bioreduction rates of two membrane-localized lipophilic spin probes, 16-doxylstearic acid methyl ester (16-DSME) and 5-doxylstearic acid
X Qi et al.
Circulation, 104(13), 1544-1549 (2001-09-26)
The maintenance and termination of reentry arrhythmias are determined by tissue properties such as refractoriness and conduction velocity. Although the effects of Na(+) and K(+) channel block on electrophysiological properties and defibrillation threshold (DFT) have been studied, little is known
Gábor Balogh et al.
PloS one, 6(6), e21182-e21182 (2011-06-24)
Cellular membranes respond rapidly to various environmental perturbations. Previously we showed that modulations in membrane fluidity achieved by heat stress (HS) resulted in pronounced membrane organization alterations which could be intimately linked to the expression and cellular distribution of heat
M A Baqué et al.
Biochemical and biophysical research communications, 505(4), 1038-1042 (2018-10-13)
Different spin labels were incorporated to the membranes of cultured insect UFL-AG-286 cells in order to characterize their physical properties by Electron Paramagnetic Resonance spectroscopy (EPR). The spectrum of the spin label 12-SASL incorporated to cell membranes was similar as those
A Grammenos et al.
Biochemical and biophysical research communications, 390(1), 5-9 (2009-09-12)
In the present work, the effect of Randomly-methylated-beta-cyclodextrin (Rameb) on the microviscosity of dimyristoyl-l-alpha phosphatidylcholine (DMPC) bilayer was investigated using the electron spin resonance (ESR) technique. The ability of Rameb to extract membrane cholesterol was demonstrated. For the first time
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