254886
6,7-二甲氧基香豆素
98%
别名:
蒿属香豆素
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关于此项目
经验公式（希尔记法）:
C11H10O4
化学文摘社编号:
分子量:
206.19
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
204-369-0
MDL number:
产品名称
6,7-二甲氧基香豆素, 98%
InChI key
GUAFOGOEJLSQBT-UHFFFAOYSA-N
InChI
1S/C11H10O4/c1-13-9-5-7-3-4-11(12)15-8(7)6-10(9)14-2/h3-6H,1-2H3
SMILES string
COc1cc2OC(=O)C=Cc2cc1OC
assay
98%
form
powder
mp
143-145 °C (lit.)
functional group
ester
Quality Level
Gene Information
mouse ... Maoa(17161)
rat ... Aldh1a2(116676)
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General description
6,7-Dimethoxycoumarin inhibits the in vitro growth of Phytophthora citrophthora, Verticillium dahliae, Penicillium digitatum, P. italicum, Colletotrichum gloeosporioides, Diplodia natalensis and Hendersonula toruloidea. Determination and pharmacokinetic study of 6,7-dimethoxycoumarin in rat plasma after intragastric administration of different decoctions of Yinchenhao Tang by reversed-phase HPLC method with UV detection has been reported.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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The antioxidant effects of chestnut inner shell extract (CISE) were investigated in a tert-butylhydroperoxide (t-BHP)-treated HepG2 cells, and in mice that were administered carbon tetrachloride (CCl(4)) and fed a high-fat diet (HFD). Pre-incubation with CISE significantly blocked the oxidative stress
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Zhi-guo Yu et al.
Journal of chromatographic science, 45(8), 544-548 (2007-11-21)
A simple and sensitive reversed-phase high-performance liquid chromatography method with UV detection is developed and validated for the determination of 6,7-dimethoxycoumarin in rat plasma and comparative analysis of its pharmacokinetics after intragastric administration of 6,7-dimethoxycoumarin and three different decoctions of
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