254940
甲基乙酰亚胺酯 盐酸盐
technical grade
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线性分子式:
CH3C(=NH)OCH3 · HCl
化学文摘社编号:
分子量:
109.55
Beilstein:
3671581
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
等级
technical grade
mp
105 °C (dec.) (lit.)
官能团
amine
储存温度
2-8°C
SMILES字符串
Cl.COC(C)=N
InChI
1S/C3H7NO.ClH/c1-3(4)5-2;/h4H,1-2H3;1H
InChI key
WHYJXXISOUGFLJ-UHFFFAOYSA-N
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一般描述
Methyl acetimidate hydrochloride is an inhibitor of N-methylation of phosphatidylethanolamine. It also prevents the stimulation of purified cardiac sarcolemmal vesicles Ca2+-pump activities.
应用
Methyl acetimidate hydrochloride has been used in pre-crystallization chemical modification of lysine residues.
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
J Armstrong et al.
The EMBO journal, 2(10), 1641-1646 (1983-01-01)
The major (gene VIII) coat protein of bacteriophage fd was radiolabelled by treating the virus with methyl[3H]acetimidate without causing any loss of infectivity. Complete amidination of lysine-8 in the amino acid sequence of the protein was achieved but little or
C Donnet et al.
The Journal of membrane biology, 163(3), 217-224 (1998-06-17)
The calcium pump of plasma membranes catalyzes the hydrolysis of ATP and phosphoric esters like p-nitrophenyl phosphate (pNPP). The latter activity requires the presence of ATP and/or calmodulin, and Ca2+ [22, 25]. We have studied the effects of nucleotide-analogues and
A J Makoff et al.
The Biochemical journal, 193(1), 245-249 (1981-01-01)
The rate of hydrolysis of the imido ester methyl acetimidate and its rate of amidination of denatured aldolase were investigated under different conditions of temperature, pH and ionic strength. Both rate constants increase greatly with temperature, whereas ionic strength has
Activation/inactivation of human angiotensin I converting enzyme following chemical modifications of amino groups near the active site.
J A Weare
Biochemical and biophysical research communications, 104(4), 1319-1326 (1982-02-26)
T L Chao et al.
Hemoglobin, 5(1), 47-72 (1981-01-01)
The contribution of the high molecular weight hemoglobin (HMW Hb) to the antisickling effect produced by treatment of sickle cell erythrocytes with methyl acetimidate (MAI) was investigated. Erythrocytes obtained from sickle cell anemia and normal individuals were incubated with varying
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