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文件

257583

8-溴辛酸

Name: 8-溴辛酸
Brand: ALDRICH

97%

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别名:

8-Bromocaprylic acid

线性分子式:

Br(CH₂)₇CO₂H

CAS号:

17696-11-6

分子量:

223.11

Beilstein:

1756103

MDL编号:

MFCD00004430

PubChem化学物质编号:

24855594

NACRES:

NA.22

检测方案

97%

reaction suitability

reagent type: cross-linking reagent

bp

147-150 °C/2 mmHg (lit.)

mp

35-37 °C (lit.)

官能团

bromo
carboxylic acid

SMILES string

OC(CCCCCCCBr)=O

InChI

1S/C8H15BrO2/c9-7-5-3-1-2-4-6-8(10)11/h1-7H2,(H,10,11)

InChI key

BKJFDZSBZWHRNH-UHFFFAOYSA-N

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一般描述

8-Bromooctanoic acid, also known as 8-bromocaprylic acid, is a cross-linking reagent. It can undergo hydrolysis to form 8-hydroxyoctanoic acid.

应用

8-Bromooctanoic acid can be used as a crosslinking reagent to:

prepare 8-mercaptooctanoic acid in the biosynthesis of lipoic acid
attach triple helix-forming oligonucleotides (TFOs) to inhibitors in their synthesis

象形图

GHS05

警示用语：

Danger

危险声明

H314

预防措施声明

P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363

危险分类

Eye Dam. 1 - Skin Corr. 1B

储存分类代码

8A - Combustible, corrosive hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

分析证书(COA)

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示例

T1503

货号

25G

包装规格/数量

其它示例：

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

输入内容 1.000309185)

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Synthesis of heteroatom-substituted analogues of stearic acid.

RA Pascal

Journal of Lipid Research, 27, 221-224 (1986)

Triple helix-forming oligonucleotides conjugated to new inhibitors of topoisomerase II: synthesis and binding properties

M Duca

Bioconjugate Chemistry, 16, 873-884 (2005)

Biosynthesis of lipoic acid: characterization of the lipoic acid auxotrophs Escherichia coli W1485-lip2 and JRG33-lip9

MA Hayden

Biochemistry, 32, 3778-3782 (1993)

Synthesis and biodistribution studies of 99m Tc labeled fatty acid derivatives prepared via "Click approach" for potential use in cardiac imaging.

Soumen Das et al.

Journal of labelled compounds & radiopharmaceuticals, 61(14), 1048-1057 (2018-09-02)

123 I-Iodophenylpentadecanoic acid (IPPA) is a metabolic agent used in nuclear medicine for diagnosis of myocardial defects. Efforts are underway worldwide to develop a 99m Tc substitute of the above radiopharmaceutical for the aforementioned application. Herein, we report synthesis and

Controlled co-release of doxorubicin and reactive oxygen species for synergistic therapy by NIR remote-triggered nanoimpellers.

Beibei Hou et al.

Materials science & engineering. C, Materials for biological applications, 74, 94-102 (2017-03-04)

How to encapsulate and transport the payload of multiple therapeutic compounds avoiding premature leakage, and simultaneously co-release them rapidly at specific lesions still remains the major concern in clinic. Herein, we designed the UCN@mSiO

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