259187
海克替啶，立体异构体混合物
别名:
5-氨基-1,3-双(2-乙己基)六氢-5-甲基嘧啶, NSC 17764
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关于此项目
经验公式（希尔记法）:
C21H45N3
化学文摘社编号:
分子量:
339.60
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
表单
liquid
折射率
n20/D 1.4649 (lit.)
沸点
160 °C/0.4 mmHg (lit.)
溶解性
acetone: soluble(lit.)
benzene: soluble(lit.)
chloroform: soluble(lit.)
ethanol: soluble(lit.)
hexane: soluble(lit.)
methanol: soluble(lit.)
petroleum ether: soluble(lit.)
water: insoluble(lit.)
密度
0.889 g/mL at 25 °C (lit.)
SMILES字符串
CCCCC(CC)CN1CN(CC(CC)CCCC)CC(C)(N)C1
InChI
1S/C21H45N3/c1-6-10-12-19(8-3)14-23-16-21(5,22)17-24(18-23)15-20(9-4)13-11-7-2/h19-20H,6-18,22H2,1-5H3
InChI key
DTOUUUZOYKYHEP-UHFFFAOYSA-N
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一般描述
已研究海克替啶嗽口水削弱龈上菌斑和牙龈炎的有效性。
应用
参与研究：
- 鉴定(identify)阿司匹林的纯液体盐形式
- 作为基于烷基的选择性置换剂候选，用于离子交换色谱法蛋白纯化
- 体内应用模型，用于试验非复制结核分枝杆菌抗性药物
- 将能量代谢从线粒体呼吸转变为糖酵解的药物的营养敏化筛选
- 血管形成抑制
- 抗疟药物筛选
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
158.0 °F - closed cup
闪点(°C)
70 °C - closed cup
个人防护装备
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
M Koray et al.
Oral diseases, 11(5), 309-313 (2005-08-27)
The aim of the present study was to compare the influence of fluconazole capsules and/or hexetidine mouthrinses for the management of oral candidiasis associated with denture stomatitis. DESIGN RELEVANT: Sixty-one patients (ages 43-76 years, mean: 61) admitted to the Department
N L Kunel'skaia et al.
Vestnik otorinolaringologii, (2)(2), 62-66 (2008-05-06)
A pilot trial of efficacy of the drugs lisobact and stomatidin in local treatment of acute pharyngitis and combined therapy of tonsillitis and paratonsillar abscess included 82 patients with tonsillitis (n=30), paratonsillar abscess (n=30) and acute pharyngitis (n=22) aged 15-72
David S Jones et al.
Pharmaceutical research, 19(6), 818-824 (2002-07-24)
Ventilator-associated pneumonia is a frequent cause of mortality in intensive care patients. This study describes the physicochemical properties of hexetidine-impregnated poly(vinyl chloride) (PVC) endotracheal tube (ET) biomaterials and their resistance to microbial adherence (Staphylococcus aureus and Pseudomonas aeruginosa). PVC emulsion
A Jouyban et al.
Die Pharmazie, 57(4), 248-249 (2002-05-10)
A non-aqueous capillary electrophoresis method has been proposed to analyse hexetidine and its degradation products in a commercial liquid pharmaceutical formulation. The separation was achieved using a 37 cm fused silica capillary with a 75 microns internal diameter, an electrolyte
M Martin et al.
Der Anaesthesist, 61(1), 25-29 (2012-01-26)
A total of three intensive care units (ICU) at a German university hospital were involved in an outbreak of Burkholderia cepacia complex (Bcc). Patients with microbiological detection of Bcc were evaluated. Products used for mouth hygiene were microbiologically tested. The
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