质量水平
方案
98%
表单
solid
反应适用性
reaction type: C-H Activation
reagent type: catalyst
沸点
174 °C/26 mmHg (lit.)
mp
60-65 °C (lit.)
SMILES字符串
Nc1cccc2cccnc12
InChI
1S/C9H8N2/c10-8-5-1-3-7-4-2-6-11-9(7)8/h1-6H,10H2
InChI key
WREVVZMUNPAPOV-UHFFFAOYSA-N
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一般描述
8-氨基喹啉在低介电常数的介质中发出中等到微弱的荧光，但在强氢键或酸性水介质中不发出荧光 。研究了 8-氨基喹啉与铬 (Ⅲ)、锰 (Ⅱ)、铁 (Ⅱ) 和 (Ⅲ)、钴 (Ⅱ)、镍 (Ⅱ)、铜 (Ⅱ)、锌 (Ⅱ)、镉 (Ⅱ) 和铂 (Ⅱ) 盐的反应。
应用
8-氨基喹啉已用于：
- 制备锇碱基稳定的末端硼烯配合物
- 分光光度法测定二价钯
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Rumei Cheng et al.
Analytical chemistry, 84(13), 5641-5644 (2012-06-05)
By incorporating the well-known fluorophore 8-aminoquinoline into graphene oxide, we have successfully prepared a turn-on fluorescent sensor capable of specific detection of D-glucosamine with a high selectivity and sensitivity. This methodology provides a new concept for the design and development
Kyalo Stephen Kanyiva et al.
Organic letters, 16(7), 1968-1971 (2014-03-22)
A palladium-catalyzed regioselective activation of C(sp(2))-H and C(sp(3))-H bonds of benzamides and carboxamides, followed by coupling with disilanes to afford organosilanes in moderate to high yields, with the aid of 8-aminoquinoline as a directing group, is reported. Catalytic C(sp(2))-H germanylation
Spectrophotometric Determination of Palladium with 8-Aminoquinoline.
Gustin VK and Sweet TR.
Analytical Chemistry, 35(1), 44-46 (1963)
Luis Carvalho et al.
Antimicrobial agents and chemotherapy, 55(9), 4204-4210 (2011-06-15)
The 8-aminoquinoline analogue sitamaquine (SQ) is an oral antileishmanial drug currently undergoing phase 2b clinical trials for the treatment of visceral leishmaniasis. In the present study, we investigated the mechanism of action of this drug in Leishmania donovani promastigotes. SQ
Some transition metal complexes of 8-aminoquinoline.
Fanning JC and Taylor LT.
J. Inorg. Nucl. Chem., 27(10), 2217-2223 (1965)
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