质量水平
方案
98%
表单
solid
反应适用性
reaction type: C-H Activation
reagent type: catalyst
沸点
174 °C/26 mmHg (lit.)
mp
60-65 °C (lit.)
SMILES字符串
Nc1cccc2cccnc12
InChI
1S/C9H8N2/c10-8-5-1-3-7-4-2-6-11-9(7)8/h1-6H,10H2
InChI key
WREVVZMUNPAPOV-UHFFFAOYSA-N
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一般描述
8-氨基喹啉在低介电常数的介质中发出中等到微弱的荧光，但在强氢键或酸性水介质中不发出荧光 。研究了 8-氨基喹啉与铬 (Ⅲ)、锰 (Ⅱ)、铁 (Ⅱ) 和 (Ⅲ)、钴 (Ⅱ)、镍 (Ⅱ)、铜 (Ⅱ)、锌 (Ⅱ)、镉 (Ⅱ) 和铂 (Ⅱ) 盐的反应。
应用
8-氨基喹啉已用于：
- 制备锇碱基稳定的末端硼烯配合物
- 分光光度法测定二价钯
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Paul Abu-Rabie et al.
Bioanalysis, 3(24), 2769-2781 (2011-12-22)
The surge in interest in switching from traditionally used wet plasma to dried matrix spot (DMS) sampling and analysis to support pharmaceutical drug development is due to the significant ethical, financial and data quality advantages on offer. Unfortunately these advantages
Fluorescence and phosphorescence of 5- and 8-aminoquinoline.
S G Schulman et al.
Analytica chimica acta, 56(1), 83-89 (1971-08-01)
Lorenz von Seidlein et al.
Malaria journal, 12, 112-112 (2013-03-30)
The diagnosis and management of glucose-6-phosphate dehydrogenase (G6PD) deficiency is a crucial aspect in the current phases of malaria control and elimination, which will require the wider use of 8-aminoquinolines for both reducing Plasmodium falciparum transmission and achieving the radical
Shyamaprosad Goswami et al.
Chemical communications (Cambridge, England), 47(32), 9101-9103 (2011-07-07)
A new fluorescence rhodamine derivative bearing an 8-aminoquinoline moiety has been designed and synthesized for selective sensing of Pd(2+) in the presence of other competing metal ions in aqueous media. Pd(2+) induced spirolactam ring opening of rhodamine is confirmed for
Liangliang Yan et al.
Journal of inorganic biochemistry, 106(1), 46-51 (2011-11-25)
Palladium(II) complexes are potential antitumor metallodrugs for their chemical resemblance to platinum(II) complexes. Two palladium(II) complexes (1 and 2) in the formula of [PdL(n)Cl] [L(1) = N-(tert-butoxycarbonyl)-l-methionine-N'-8-quinolylamide, L(2) = L-alanine-N'-8-quinolylamide] have been synthesized accordingly. The structures of the complexes were
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