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Merck
CN

262102

5,6-二氢-2H-吡喃-2-酮

technical grade, 90%

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关于此项目

经验公式(希尔记法):
C5H6O2
化学文摘社编号:
分子量:
98.10
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1610
Assay:
90%
Form:
liquid
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产品名称

5,6-二氢-2H-吡喃-2-酮, technical grade, 90%

InChI

1S/C5H6O2/c6-5-3-1-2-4-7-5/h1,3H,2,4H2

SMILES string

O=C1OCCC=C1

InChI key

QBDAFARLDLCWAT-UHFFFAOYSA-N

grade

technical grade

assay

90%

form

liquid

refractive index

n20/D 1.483 (lit.)

bp

103 °C/10 mmHg (lit.)

density

1.139 g/mL at 25 °C (lit.)

functional group

ester

storage temp.

2-8°C

Quality Level

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Application

5,6-二氢-2H-吡喃-2-酮已用于制备:
  • (1 aR ,5 aR ,5 bS ,6 S ,7 S )-6,7-二- 叔丁基-5-氧代-吡咯烷 [1,2- b 异恶唑烷[4,5- c 四氢吡喃
  • 4-(苯基)四氢-2 H -吡喃-2-酮

General description

已有报道将格氏试剂对映选择性共轭加成到手性膦-铜碘化物催化剂催化的5,6-二氢-2H-吡喃-2-酮上。

pictograms

Flame

signalword

Warning

hcodes

Hazard Classifications

Flam. Liq. 3

存储类别

3 - Flammable liquids

wgk

WGK 3

flash_point_f

114.8 °F - closed cup

flash_point_c

46 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

危险化学品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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D Socha et al.
Carbohydrate research, 336(4), 315-318 (2001-12-01)
(1aR,5aR,5bS,6S,7S)-6,7-Di-tert-butoxy-5-oxo-pyrrolidino[1,2-b]isoxazolidino[4,5-c]tetrahydropyran (8) prepared by (1,3)-dipolar cycloaddition of the cyclic nitrone 6 derived from tartaric acid to 5,6-dihydro-2H-pyran-2-one (7) was transformed into indolizidine 11 via a sequence of reactions involving methanolysis of the lactone ring, intramolecular alkylation of the nitrogen atom
Conjugate addition of diethylzinc to a, ?-unsaturated lactones catalyzed by copper-phosphite complexes.
Yan M, et al.
Chemical Communications (Cambridge, England), 2, 115-116 (2000)
Rhodium-catalyzed asymmetric 1, 4-addition of arylboron reagents to α,β-unsaturated esters.
Takaya Y, et al.
Tetrahedron Asymmetry, 10(20), 4047-4056 (1999)
Fabrizio Carta et al.
Bioorganic & medicinal chemistry letters, 22(1), 267-270 (2011-12-06)
The inhibition of the zinc enzyme carbonic anhydrase (CA, EC 4.2.1.1) with (thio)coumarins has been recently reported (Maresca et al., J. Am. Chem. Soc. 2009, 131, 3057). Here we demonstrate that a series of γ- and δ-(thio)lactones also act as

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