264415
2,4-二氟苄基溴
98%
别名:
α-溴-2,4-二氟甲苯
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关于此项目
线性分子式:
F2C6H3CH2Br
化学文摘社编号:
分子量:
207.02
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
245-938-3
MDL number:
Assay:
98%
Form:
liquid
InChI key
IBLMYGXJKQIGSN-UHFFFAOYSA-N
InChI
1S/C7H5BrF2/c8-4-5-1-2-6(9)3-7(5)10/h1-3H,4H2
SMILES string
Fc1ccc(CBr)c(F)c1
assay
98%
form
liquid
refractive index
n20/D 1.525 (lit.)
density
1.613 g/mL at 25 °C (lit.)
functional group
bromo, fluoro
Application
2,4-Difluorobenzyl bromide has been used in the preparation of:
- novel 1,2,4-triazolium derivatives
- 1,5-biaryl pyrrole EP1 receptor antagonists
signalword
Danger
hcodes
Hazard Classifications
Flam. Liq. 3 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1
存储类别
3 - Flammable liquids
wgk
WGK 3
flash_point_f
104.0 °F - closed cup
flash_point_c
40 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
新产品
此项目有
Adrian Hall et al.
Bioorganic & medicinal chemistry letters, 16(14), 3657-3662 (2006-05-16)
The preliminary SAR of a series of novel 1,5-biaryl pyrrole EP1 receptor antagonists derived from compound 1 is described. Replacement of the benzyl group of 1 with isosteric groups was investigated. The most effective replacement was found to be the
Yan Luo et al.
Archiv der Pharmazie, 342(7), 386-393 (2009-06-23)
A series of novel 1,2,4-triazolium derivatives was synthesized starting from commercially available 1H-1,2,4-triazole, 2,4-dichlorobenzyl chloride, or 2,4-difluorobenzyl bromide. Their antibacterial and antifungal activities were evaluated against Staphylococcus aureus ATCC 29213, Escherichia coli ATCC 25922, Bacillus proteus, Bacillus subtilis, Pseudomonas aeruginosa
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