268615
3-氨基丙基磷酸
98%
别名:
β-氨基丙基膦酸, 3-氨丙基(羟基)膦酸盐, 3-氨基丙基磷酸, 3-氨基丙烷-1-膦酸, P-（3-氨丙基）膦酸
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关于此项目
线性分子式:
H2N(CH2)3P(O)(OH)2
化学文摘社编号:
分子量:
139.09
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
98%
Form:
solid
InChI
1S/C3H10NO3P/c4-2-1-3-8(5,6)7/h1-4H2,(H2,5,6,7)
SMILES string
NCCCP(O)(O)=O
InChI key
GSZQTIFGANBTNF-UHFFFAOYSA-N
assay
98%
form
solid
mp
294 °C (dec.) (lit.)
functional group
amine
Quality Level
Gene Information
rat ... Gabbr1(81657)
General description
通过测量由非特异性AuNP吸附引起的肼的电催化阳极电流，可检查DNA偶联的金纳米颗粒（AuNP）与用3-氨基丙基膦酸修饰的铟-锡氧化物电极的相对非特异性结合。
Application
3-氨基丙基膦酸被用作GABA（C）受体的选择性拮抗剂。
Biochem/physiol Actions
GABAB 受体激动剂；基础催乳素分泌拮抗剂。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
D I Kerr et al.
Brain research, 480(1-2), 312-316 (1989-02-20)
Baclofen, 3-amino-propylphosphonic acid (3-APPA), and beta-phenyl-GABA (BPG), each reduced the frequency of spontaneous paroxysmal discharges in rat neocortical slices maintained in Mg2+-free medium, reversibly antagonised by phaclofen and 4-amino-butylphosphonic acid (4-ABPA). At lower concentrations, not influencing the discharges, both 3-APPA
H Dong et al.
Gastroenterology, 118(2), 328-336 (2000-01-29)
This study aimed to show the presence of deglutitive and distal inhibition in the rat esophagus and to differentiate the underlying neural mechanisms. Under urethane anesthesia, the pharyngoesophageal tract was fitted with water-filled balloons for luminal distention and pressure recording.
New magnetic resonance imaging contrast agents for infarct imaging based on phosphonate derivatives of Gd-DTPA.
I K Adzamli et al.
Investigative radiology, 26 Suppl 1, S242-S244 (1991-11-01)
Maria Teresa Cambria et al.
International journal of molecular sciences, 21(22) (2020-11-15)
Combined treatments which use nanoparticles and drugs could be a synergistic strategy for the treatment of a variety of cancers to overcome drug resistance, low efficacy, and high-dose-induced systemic toxicity. In this study, the effects on human colon adenocarcinoma cells
Hsueh-Hsia Wu et al.
Sensors (Basel, Switzerland), 18(12) (2018-12-21)
Bacteriorhodopsin-embedded purple membranes (PM) have been demonstrated to be a sensitive photoelectric transducer for microbial detection. To efficiently prepare versatile BR-based immunosensors with protein A as antibody captures, a large, high-coverage, and uniformly oriented PM monolayer was fabricated on an
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