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Merck
CN

268615

3-氨基丙基磷酸

98%

别名:

β-氨基丙基膦酸, 3-氨丙基(羟基)膦酸盐, 3-氨基丙基磷酸, 3-氨基丙烷-1-膦酸, P-(3-氨丙基)膦酸

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关于此项目

线性分子式:
H2N(CH2)3P(O)(OH)2
化学文摘社编号:
分子量:
139.09
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
98%
Form:
solid
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InChI

1S/C3H10NO3P/c4-2-1-3-8(5,6)7/h1-4H2,(H2,5,6,7)

SMILES string

NCCCP(O)(O)=O

InChI key

GSZQTIFGANBTNF-UHFFFAOYSA-N

assay

98%

form

solid

mp

294 °C (dec.) (lit.)

functional group

amine

Quality Level

Gene Information

rat ... Gabbr1(81657)

General description

通过测量由非特异性AuNP吸附引起的肼的电催化阳极电流,可检查DNA偶联的金纳米颗粒(AuNP)与用3-氨基丙基膦酸修饰的铟-锡氧化物电极的相对非特异性结合

Application

3-氨基丙基膦酸被用作GABA(C)受体的选择性拮抗剂

Biochem/physiol Actions

GABAB 受体激动剂;基础催乳素分泌拮抗剂。

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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D I Kerr et al.
Brain research, 480(1-2), 312-316 (1989-02-20)
Baclofen, 3-amino-propylphosphonic acid (3-APPA), and beta-phenyl-GABA (BPG), each reduced the frequency of spontaneous paroxysmal discharges in rat neocortical slices maintained in Mg2+-free medium, reversibly antagonised by phaclofen and 4-amino-butylphosphonic acid (4-ABPA). At lower concentrations, not influencing the discharges, both 3-APPA
H Dong et al.
Gastroenterology, 118(2), 328-336 (2000-01-29)
This study aimed to show the presence of deglutitive and distal inhibition in the rat esophagus and to differentiate the underlying neural mechanisms. Under urethane anesthesia, the pharyngoesophageal tract was fitted with water-filled balloons for luminal distention and pressure recording.
New magnetic resonance imaging contrast agents for infarct imaging based on phosphonate derivatives of Gd-DTPA.
I K Adzamli et al.
Investigative radiology, 26 Suppl 1, S242-S244 (1991-11-01)
Maria Teresa Cambria et al.
International journal of molecular sciences, 21(22) (2020-11-15)
Combined treatments which use nanoparticles and drugs could be a synergistic strategy for the treatment of a variety of cancers to overcome drug resistance, low efficacy, and high-dose-induced systemic toxicity. In this study, the effects on human colon adenocarcinoma cells
Hsueh-Hsia Wu et al.
Sensors (Basel, Switzerland), 18(12) (2018-12-21)
Bacteriorhodopsin-embedded purple membranes (PM) have been demonstrated to be a sensitive photoelectric transducer for microbial detection. To efficiently prepare versatile BR-based immunosensors with protein A as antibody captures, a large, high-coverage, and uniformly oriented PM monolayer was fabricated on an

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