assay
98%
mp
85-89 °C (lit.)
SMILES string
CS(N)(=O)=O
InChI
1S/CH5NO2S/c1-5(2,3)4/h1H3,(H2,2,3,4)
InChI key
HNQIVZYLYMDVSB-UHFFFAOYSA-N
法规信息
新产品
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Roberto Anacardio et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 877(22), 2087-2092 (2009-06-23)
A sensitive and selective liquid chromatographic method coupled with tandem mass spectrometry (LC-MS/MS) was developed and validated for the quantification of methanesulfonamide (MSA) in human urine. MSA is a potential in vivo metabolite of reparixin, a specific inhibitor of the
Sevgi Karakuş et al.
European journal of medicinal chemistry, 44(9), 3591-3595 (2009-03-28)
Due to a continuing effort to develop new antiviral agents, a series of 1-[4-(methanesulfonamido)-3-phenoxyphenyl]-3-alkyl/aryl thioureas 3a-i have been synthesized by the reaction of alkyl/aryl isothiocyanates with 4-amino-2-phenoxymethanesulfonanilide. These derivatives were structurally characterized by the use of spectral techniques and evaluated
Jean-Yves Winum et al.
Bioorganic & medicinal chemistry letters, 15(9), 2353-2358 (2005-04-20)
A small library of N-hydroxysulfamides was synthesized by an original approach in order to investigate whether this zinc-binding function is efficient for the design of inhibitors targeting the cytosolic (hCA I and II) and transmembrane, tumor-associated (hCA IX and XII)
Sunil Kumar Singh et al.
Bioorganic & medicinal chemistry letters, 14(7), 1683-1688 (2004-03-18)
The effect of methanesulfonamide (MeSO(2)NH) group on COX-2 inhibitory activity of 1,5-diarylpyrazole is described. While this group being at position-4 of the N(1)-phenyl ring was found to be ineffective, its installation at position-4 of the C-5 phenyl ring offered several
Mariya al-Rashida et al.
Bioorganic & medicinal chemistry, 19(11), 3367-3371 (2011-05-11)
Series of chromone containing sulfonamides were prepared by the reaction of (un)substituted 3-formylchromones with 3-aminobenzenesulfonamide and 4-aminobenzenesulfonamide. Bovine carbonic anhydrase (bCA) inhibitory activity of these newly synthesized compounds was determined. All compounds were active and possessed excellent bCA inhibitory activities
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