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Merck
CN

270873

2-羟基喹啉

98%

别名:

2-喹啉醇, 喹诺酮

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关于此项目

经验公式(希尔记法):
C9H7NO
化学文摘社编号:
分子量:
145.16
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
200-420-6
MDL number:
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产品名称

2-羟基喹啉, 98%

InChI key

LISFMEBWQUVKPJ-UHFFFAOYSA-N

InChI

1S/C9H7NO/c11-9-6-5-7-3-1-2-4-8(7)10-9/h1-6H,(H,10,11)

SMILES string

Oc1ccc2ccccc2n1

assay

98%

form

crystals

mp

198-199 °C (lit.)

solubility

alcohol: soluble(lit.)
diethyl ether: soluble(lit.)
dilute HCl: soluble(lit.)
water: slightly soluble (1 g/950mL)(lit.)

Quality Level

Application

2-羟基喹啉用于获得具有向较长波长偏移的强波段的铂(IV)配合物的设计。Pt(IV)配合物是惰性稳定的前药,可被光激活,产生具有潜在抗癌活性的 Pt(II)物质

General description

2-羟基喹啉是噬菌体对氧磷酶 1(PON1)的特异性抑制剂

pictograms

CorrosionExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

新产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Arianna Friggeri et al.
Journal of controlled release : official journal of the Controlled Release Society, 97(2), 241-248 (2004-06-16)
Gels of low molecular weight gelators (LMWGs) are self-assembled, thermoreversible, viscoelastic materials which can also be rendered sensitive to light, pH or chemical substances by simple chemical modifications. In addition, the ability of some of these LMWGs to gelate water
Kamya Bhatnagar et al.
PloS one, 14(11), e0224650-e0224650 (2019-11-07)
The evolution of antibiotic resistance is influenced by a variety of factors, including the availability of resistance mutations, and the pleiotropic effects of such mutations. Here, we isolate and characterize chromosomal quinolone resistance mutations in E. coli, in order to
Elad Cohen et al.
Journal of lipids, 2012, 762560-762560 (2012-06-13)
Human carotid plaque components interact directly with circulating blood elements and thus they might affect each other. We determined plaque paraoxonase1 (PON1) hydrolytic-catalytic activity and compared plaque and blood levels of lipids, HDL, PON1, and HbA1c, as well as plaque-oxidized
Elizabeth M Wagner et al.
Angiogenesis, 18(1), 1-11 (2014-08-26)
Expanded and aberrant bronchial vascularity, a prominent feature of the chronic asthmatic airway, might explain persistent airway wall edema and sustained leukocyte recruitment. Since it is well established that there are causal relationships between exposure to house dust mite (HDM)
Antonios Keirouz et al.
Journal of nanobiotechnology, 18(1), 51-51 (2020-03-20)
The state-of-the-art hernia meshes, used in hospitals for hernia repair, are predominantly polymeric textile-based constructs that present high mechanical strength, but lack antimicrobial properties. Consequently, preventing bacterial colonization of implanted prosthetic meshes is of major clinical relevance for patients undergoing

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