272361
2,3-二氨基甲苯
97%
别名:
2,3-二氨基甲苯
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关于此项目
线性分子式:
CH3C6H3(NH2)2
化学文摘社编号:
分子量:
122.17
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
220-248-5
Beilstein/REAXYS Number:
907184
MDL number:
产品名称
2,3-二氨基甲苯, 97%
InChI key
AXNUJYHFQHQZBE-UHFFFAOYSA-N
InChI
1S/C7H10N2/c1-5-3-2-4-6(8)7(5)9/h2-4H,8-9H2,1H3
SMILES string
Cc1cccc(N)c1N
assay
97%
mp
59-65 °C (lit.)
Quality Level
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General description
The antitumour activity of Pd(II) and Pt(II) new complexes with 2,3-diaminotoluene was studied. 2,3-Diaminotoluene induced CYP1A activity.
signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
M Pérez-Cabré et al.
Journal of inorganic biochemistry, 98(3), 510-521 (2004-02-28)
Pd(II) and Pt(II) new complexes with simple aromatic diamines were synthesised and characterised with the aim of studying their possible antitumour activity. The aromatic diamines chosen were 2,3-diaminotoluene (2,3 dat), 3,4-diaminotoluene (3,4 dat), 4,5-diaminoxylene (4,5 dax) and 2,3-diaminophenol (2,3 dap).
Y L Cheung et al.
Toxicology and applied pharmacology, 139(1), 203-211 (1996-07-01)
The present study was undertaken to provide a rationale for the marked difference in carcinogenic potential among isomeric diaminotoluenes, in relation to their ability to induce their own bioactivation through CYP1A induction, their genotoxic potential, and their ability to bind
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