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Merck
CN

272361

2,3-二氨基甲苯

97%

别名:

2,3-二氨基甲苯

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关于此项目

线性分子式:
CH3C6H3(NH2)2
化学文摘社编号:
分子量:
122.17
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
220-248-5
Beilstein/REAXYS Number:
907184
MDL number:
Assay:
97%
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Quality Level

assay

97%

mp

59-65 °C (lit.)

SMILES string

Cc1cccc(N)c1N

InChI

1S/C7H10N2/c1-5-3-2-4-6(8)7(5)9/h2-4H,8-9H2,1H3

InChI key

AXNUJYHFQHQZBE-UHFFFAOYSA-N

General description

The antitumour activity of Pd(II) and Pt(II) new complexes with 2,3-diaminotoluene was studied. 2,3-Diaminotoluene induced CYP1A activity.


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signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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M Pérez-Cabré et al.
Journal of inorganic biochemistry, 98(3), 510-521 (2004-02-28)
Pd(II) and Pt(II) new complexes with simple aromatic diamines were synthesised and characterised with the aim of studying their possible antitumour activity. The aromatic diamines chosen were 2,3-diaminotoluene (2,3 dat), 3,4-diaminotoluene (3,4 dat), 4,5-diaminoxylene (4,5 dax) and 2,3-diaminophenol (2,3 dap).
Y L Cheung et al.
Toxicology and applied pharmacology, 139(1), 203-211 (1996-07-01)
The present study was undertaken to provide a rationale for the marked difference in carcinogenic potential among isomeric diaminotoluenes, in relation to their ability to induce their own bioactivation through CYP1A induction, their genotoxic potential, and their ability to bind



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货号GTIN
272361-5G04061826144206