27370
辛可宁
crystallized, ≥98.0% (NT)
别名:
NSC 6176
登录 查看组织和合同定价。
选择规格
变更视图
关于此项目
经验公式（希尔记法）:
C19H22N2O
化学文摘社编号:
分子量:
294.39
EC Number:
204-234-6
Beilstein/REAXYS Number:
89689
UNSPSC Code:
12352104
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Quality Segment
assay
≥98.0% (NT)
form
powder
optical activity
[α]20/D +225±5°, c = 0.5% in ethanol
quality
crystallized
impurities
~15% dihydrocinchonine (HPLC)
mp
260-263 °C
functional group
hydroxyl
SMILES string
O[C@H]([C@H]1C[C@@H]2CCN1C[C@@H]2C=C)c3ccnc4ccccc34
InChI
1S/C19H22N2O/c1-2-13-12-21-10-8-14(13)11-18(21)19(22)16-7-9-20-17-6-4-3-5-15(16)17/h2-7,9,13-14,18-19,22H,1,8,10-12H2/t13-,14-,18+,19-/m0/s1
InChI key
KMPWYEUPVWOPIM-QAMTZSDWSA-N
Gene Information
human ... CYP2D6(1565)
General description
Cinchonine is a cinchona alkaloid generally found in the bark of Cinchona officinalis plants. It is a pseudoenantiomer that is commonly employed in malaria therapy. Cinchonine is also used as an organocatalyst in many asymmetric reactions.
Application
Cinchonine can be used:
- As a substrate in the study of supercritical fluid chromatography (SFC) parameters in pharmaceutical analysis.
- To prepare possible butyrylcholinesterase inhibitors.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Skin Sens. 1A
存储类别
11 - Combustible Solids
wgk
WGK 1
ppe
dust mask type N95 (US), Eyeshields, Gloves