274194
3,4,5-三羟基苯甲酸甲酯
98%
别名:
没食子酸甲酯
质量水平
方案
98%
mp
201-203 °C (lit.)
SMILES字符串
COC(=O)c1cc(O)c(O)c(O)c1
InChI
1S/C8H8O5/c1-13-8(12)4-2-5(9)7(11)6(10)3-4/h2-3,9-11H,1H3
InChI key
FBSFWRHWHYMIOG-UHFFFAOYSA-N
一般描述
3,4,5-三羟基苯甲酸甲酯，又称没食子酸甲酯，是没食子酸的衍生物，含有三个羟基和一个酯键，带来反应性和有机溶剂溶解性。它具有较强的自由基清除活性，可有效地防止生物系统氧化应激和延长材料寿命。天然来源和低毒性令其适合生物医学应用，特别是药物递送和组织工程领域。
应用
3,4,5-三羟基苯甲酸甲酯可用于：
- 作为前体合成肺癌治疗用纳米复合物药物递送系统。它低毒性，并可通过生成自由基诱导细胞凋亡。
- 作为起始材料经由开环复分解聚合反应(ROMP)制备降冰片烯基主链聚合物，用于制作生物医用涂层和电子元件。
- 作为蔗渣预处理的添加剂，改善生物质源木质素的去除及纤维素水解。有助于从生物质中获得各种生物技术用能量货币。
警示用语：
Warning
危险分类
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Judith Delius et al.
PloS one, 12(9), e0184487-e0184487 (2017-09-09)
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Rayza Morganna Farias Cavalcanti et al.
3 Biotech, 8(6), 270-270 (2018-06-06)
One of the tannase isoforms produced by the fungus Aspergillus fumigatus CAS-21 under submerged fermentation (SbmF) was purified 4.9-fold with a 10.2% recovery. The glycoprotein (39.1% carbohydrate content) showed an estimated molecular mass of 60 kDa. Optimum temperature and pH for
Liangliang Zhang et al.
International journal of molecular sciences, 19(10) (2018-10-14)
In the present paper, methyl gallate (MeG), a simple polyphenol and also the monomer of hydrolysable tannins, was selected to study the deprotonation process for the hydroxyls of the galloyl group by the combined use of spectroscopic measurements and quantum
James A G Crispo et al.
Biochemical and biophysical research communications, 393(4), 773-778 (2010-02-23)
Neurodegenerative disorders are a class of diseases that have been linked to apoptosis induced by elevated levels of reactive oxygen species (ROS). ROS activates the apoptotic cascade through mitochondrial dysfunction and damage to lipids, proteins and DNA. Recently, fruit and
J P Chu et al.
Journal of dentistry, 35(5), 383-387 (2007-01-02)
To evaluate the effect of compounds of Galla chinensis on the remineralisation of initial enamel carious lesions in vitro. Sixty bovine enamel blocks with early lesions were prepared and randomly divided into six treatment groups. The lesions were subjected to
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