274313
弗罗利辛 二水合物
99%
别名:
1-[2-(β-D-吡喃葡糖基氧)-4,6-二羟基苯基]-3-(4-羟基苯基)-1-丙酮, 根皮素2′-β-D-吡喃葡萄糖苷, 根皮素2′-β-D-葡萄糖苷, 根皮苷 二水合物
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关于此项目
经验公式（希尔记法）:
C21H24O10 · 2H2O
化学文摘社编号:
分子量:
472.44
UNSPSC Code:
12352205
NACRES:
NA.22
PubChem Substance ID:
EC Number:
200-487-1
Beilstein/REAXYS Number:
66621
MDL number:
产品名称
弗罗利辛 二水合物, 99%
InChI key
XQWBNXSENPTIDY-YXMARJSJSA-N
InChI
1S/C21H24O10.2H2O/c22-9-16-18(27)19(28)20(29)21(31-16)30-15-8-12(24)7-14(26)17(15)13(25)6-3-10-1-4-11(23)5-2-10;;/h1-2,4-5,7-8,16,18-24,26-29H,3,6,9H2;2*1H2/t16-,18-,19+,20-,21-;;/m1../s1
SMILES string
O.O.OC[C@H]1O[C@@H](Oc2cc(O)cc(O)c2C(=O)CCc3ccc(O)cc3)[C@H](O)[C@@H](O)[C@@H]1O
assay
99%
form
powder
optical activity
[α]20/D −52°, c = 3 in ethanol
mp
113-114 °C (lit.)
Quality Level
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Features and Benefits
用于诱导实验性糖尿。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Rune E Kuhre et al.
Diabetologia, 62(6), 1011-1023 (2019-03-25)
Sodium-glucose cotransporter (SGLT) 2 inhibitors constitute a new class of glucose-lowering drugs, but they increase glucagon secretion, which may counteract their glucose-lowering effect. Previous studies using static incubation of isolated human islets or the glucagon-secreting cell line α-TC1 suggested that
Eric Dale Buras et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(8), 3537-3548 (2015-05-09)
Adipose tissue macrophages (ATMs) play an important role in the pathogenesis of obese type 2 diabetes. High-fat diet (HFD)-induced obesity has been shown to lead to ATM accumulation in rodents; however, the impact of hyperglycemia on ATM dynamics in HFD-fed
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