产品名称
三异丁基硅烷, 99%
InChI
1S/C12H28Si/c1-10(2)7-13(8-11(3)4)9-12(5)6/h10-13H,7-9H2,1-6H3
SMILES string
CC(C)C[SiH](CC(C)C)CC(C)C
InChI key
BORQTRQJFUNMBC-UHFFFAOYSA-N
assay
99%
refractive index
n20/D 1.435 (lit.)
bp
204-206 °C (lit.)
density
0.764 g/mL at 25 °C (lit.)
Quality Level
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Application
Triisobutylsilane can be used as a reagent in combination with trifluoroacetic acid (TFA) for the deprotection of the Fmoc functional group.
General description
Triisobutylsilane (TIBS) is a versatile organosilicon compound that finds several applications in organic synthesis. Some of its common applications include desulfurization, deprotection of the N-boc group, and radical reactions.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
228.2 °F - closed cup
flash_point_c
109 °C - closed cup
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Pingping Shen et al.
Molecular neurobiology, 58(1), 21-33 (2020-09-06)
Alteration in cellular prion protein (PrPC) localization on the cell surface through mediation of the glycosylphosphatidylinositol (GPI) anchor has been reported to dramatically affect the formation and infectivity of its pathological isoform (PrPSc). A patient with Gerstmann-Sträussler-Scheinker (GSS) syndrome was
Thorsten Krause et al.
Frontiers in immunology, 11, 565243-565243 (2020-10-30)
Immunoglobulin E (IgE) is pivotal for manifestation and persistence of most immediate-type allergies and some asthma phenotypes. Consequently, IgE represents a crucial target for both, diagnostic purposes as well as therapeutic approaches. In fact, allergen-specific immunotherapy - aiming to re-route
Da Sun et al.
Bioconjugate chemistry, 30(3), 667-678 (2018-12-26)
CRISPR/Cas9 system is a promising approach for gene editing in gene therapy. Effective gene editing requires safe and efficient delivery of CRISPR/Cas9 system in target cells. Several new multifunctional pH-sensitive amino lipids were designed and synthesized with modification of the
Rongbing Yang et al.
Molecular pharmaceutics, 14(1), 252-263 (2017-01-04)
Desired characteristics of nanocarriers are crucial to explore its therapeutic potential. This investigation aimed to develop tunable bioresponsive newly synthesized unique arginine grafted poly(cystaminebis(acrylamide)-diaminohexane) [ABP] polymeric matrix based nanocarriers by using L9 Taguchi factorial design, desirability function, and multivariate method.
Thorsten Krause et al.
mAbs, 9(2), 333-341 (2016-12-03)
In chronic inflammatory airway diseases, mucins display disease-related alterations in quantity, composition and glycosylation. This opens the possibility to diagnose and monitor inflammatory airway disorders and their exacerbation based on mucin properties. For such an approach to be reasonably versatile
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