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279552

4-氯-3-乙基苯酚

Name: 4-氯-3-乙基苯酚
Brand: ALDRICH

97%

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关于此项目

线性分子式:

ClC₆H₃(C₂H₅)OH

化学文摘社编号:

14143-32-9

分子量:

156.61

NACRES:

NA.22

PubChem Substance ID:

24856895

UNSPSC Code:

12352100

EC Number:

237-991-6

MDL number:

MFCD00010822

Assay:

97%

Form:

solid

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属性

assay

97%

form

solid

mp

45-50 °C (lit.)

functional group

chloro

SMILES string

CCc1cc(O)ccc1Cl

InChI

1S/C8H9ClO/c1-2-6-5-7(10)3-4-8(6)9/h3-5,10H,2H2,1H3

InChI key

DVKVZPIRWWREJC-UHFFFAOYSA-N

说明

Application

4-Chloro-3-ethylphenol is a ryanodine receptor antagonist and is commonly used as research tool and diagnostic reagent for malignant hyperthermia.

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Superficial buffer barrier and preferentially directed release of Ca2+ in canine airway smooth muscle.

L J Janssen et al.

The American journal of physiology, 276(5 Pt 1), L744-L753 (1999-05-18)

We examined cytosolic concentration of Ca2+ ([Ca2+]i) in canine airway smooth muscle using fura 2 fluorimetry (global changes in [Ca2+]i), membrane currents (subsarcolemmal [Ca2+]i), and contractions (deep cytosolic [Ca2+]i). Acetylcholine (10(-4) M) elicited fluorimetric, electrophysiological, and mechanical responses. Caffeine (5

Dynamic imaging of endoplasmic reticulum Ca2+ concentration in insulin-secreting MIN6 Cells using recombinant targeted cameleons: roles of sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA)-2 and ryanodine receptors.

Aniko Varadi et al.

Diabetes, 51 Suppl 1, S190-S201 (2002-01-30)

The endoplasmic reticulum (ER) plays a pivotal role in the regulation of cytosolic Ca(2+) concentrations ([Ca(2+)](cyt)) and hence in insulin secretion from pancreatic beta-cells. However, the molecular mechanisms involved in both the uptake and release of Ca(2+) from the ER

Actions of 4-chloro-3-ethyl phenol on internal Ca2+ stores in vascular smooth muscle and endothelial cells.

A M Low et al.

British journal of pharmacology, 122(3), 504-510 (1997-11-14)

1. Recently, 4-chloro-3-ethyl phenol (CEP) has been shown to cause the release of internally stored Ca2+ apparently through ryanodine-sensitive Ca2+ channels, in fractionated skeletal muscle terminal cisternae and in a variety of non-excitable cell types. Its action on smooth muscle

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全球贸易项目编号

货号	GTIN
279552-25G	04061832279732