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Merck
CN

280135

2-[4-(二甲氨基)苯乙烯基]-1-甲基吡啶碘

Dye content 95 %

别名:

2-Di-1-ASP

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关于此项目

经验公式（希尔记法）:
C16H19IN2
化学文摘社编号:
2156-29-8
分子量:
366.24
UNSPSC Code:
12352103
NACRES:
NA.23
PubChem Substance ID:
57648287
EC Number:
218-460-8
Beilstein/REAXYS Number:
3776369
MDL number:
MFCD00011980

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产品名称

2-[4-(二甲氨基)苯乙烯基]-1-甲基吡啶碘, Dye content 95 %

InChI key

XPOIQAIBZGSIDD-UHFFFAOYSA-M

InChI

1S/C16H19N2.HI/c1-17(2)15-10-7-14(8-11-15)9-12-16-6-4-5-13-18(16)3;/h4-13H,1-3H3;1H/q+1;/p-1

SMILES string

[I-].CN(C)c1ccc(cc1)\C=C\c2cccc[n+]2C

form

solid

composition

Dye content, 95%

mp

280 °C (dec.) (lit.)

λmax

466 nm

fluorescence

λex 466 nm; λem 504 nm in methanol
λex 475 nm; λem 589 nm in methanol

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Application

DASPMI广泛用于活细胞中线粒体的选择性染色。
DASPMI是一种极性敏感染料，可测量活细胞中线粒体的膜电位。它可以在基于光引发剂的系统的开发中用作光吸收剂。

General description

2-[4-（二甲基氨基）苯乙烯基]-1-甲基碘化吡啶（DASPMI）是一种线粒体染色苯乙烯基染料，用于通过施加跨膜电位的变化来产生快速响应机制。DASPMI可以用作低毒性染色剂，显示线粒体的荧光行为。

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCL8555
MKBR0101V
04305MX
11620DD

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The journal of physical chemistry. B, 116(8), 2464-2471 (2012-02-07)
We report an interesting pH-tunable energy transfer between an acceptor ionic styryl dye 2-(4-(dimethylamino)styryl)-1-methylpyridinium iodide and a donor charge-transfer dye 1,8-naphthalimide in a vesicular medium. The polyethylene-b-polyethylene glycol block copolymer intercalates with the sodium dodecyl sulfate anionic surfactant to form
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The journal of physical chemistry. B, 116(17), 5226-5233 (2012-04-18)
This paper reports an interesting transformation of binding mode of 2-(4-(dimethylamino)styryl)-1-methylpyridinium iodide (DASPMI) with calf thymus DNA from minor groove binding in buffer solution to intercalative binding when the dye is encapsulated inside a vesicle formed by the interaction of
S C Chang et al.
The Journal of biological chemistry, 273(24), 14933-14941 (1998-06-17)
In eukaryotic cells, cardiolipin (CL) synthase catalyzes the final step in the synthesis of CL from phosphatidylglycerol and CDP-diacylglycerol. CL and its synthesis are localized predominantly to the mitochondrial inner membrane, and CL is generally thought to be an essential
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