280135
2-[4-(二甲氨基)苯乙烯基]-1-甲基吡啶碘
Dye content 95 %
别名:
2-Di-1-ASP
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关于此项目
经验公式（希尔记法）:
C16H19IN2
化学文摘社编号:
分子量:
366.24
UNSPSC Code:
12352103
NACRES:
NA.23
PubChem Substance ID:
EC Number:
218-460-8
Beilstein/REAXYS Number:
3776369
MDL number:
InChI key
XPOIQAIBZGSIDD-UHFFFAOYSA-M
InChI
1S/C16H19N2.HI/c1-17(2)15-10-7-14(8-11-15)9-12-16-6-4-5-13-18(16)3;/h4-13H,1-3H3;1H/q+1;/p-1
SMILES string
[I-].CN(C)c1ccc(cc1)\C=C\c2cccc[n+]2C
form
solid
composition
Dye content, 95%
mp
280 °C (dec.) (lit.)
λmax
466 nm
fluorescence
λex 466 nm; λem 504 nm in methanol, λex 475 nm; λem 589 nm in methanol
General description
2-[4-（二甲基氨基）苯乙烯基]-1-甲基碘化吡啶（DASPMI）是一种线粒体染色苯乙烯基染料，用于通过施加跨膜电位的变化来产生快速响应机制。DASPMI可以用作低毒性染色剂，显示线粒体的荧光行为。
Application
DASPMI广泛用于活细胞中线粒体的选择性染色。
DASPMI是一种极性敏感染料，可测量活细胞中线粒体的膜电位。它可以在基于光引发剂的系统的开发中用作光吸收剂。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Dimethylaminostyrylmethylpyridiniumiodine (DASPMI) as a fluorescent probe for mitochondria in situ
Bereiter-Hahn J, et al.
Biochimica et Biophysica Acta, 423(1), 1-14 (1976)
G P Gorbenko et al.
Biofizika, 38(4), 699-702 (1993-07-01)
Using fluorescent probe 4-(n-dimethyl-aminostyryl)-1-methyl-pyridine (DSM) the effect of electrons with the energy 5 MeV on the structure of erythrocyte membrane has been investigated. It was found that in the irradiated erythrocyte ghosts the number of DSM binding sites increases. Irradiation
M V Smelianskaia et al.
Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993), 59(3), 86-90 (1997-05-01)
The scientific investigations conducted first allow using a method of fluorescent probes for the diagnosis of human coronaviral intestinal infection. The method is characterised by sensitivity, specificity, reproductivity and proximity. It is comparable, according to these parameters, with the methods
Aged mother cells of Saccharomyces cerevisiae show markers of oxidative stress and apoptosis
Laun P, et al.
Molecular Biology, 39(5), 1166-1173 (2001)
Photophysical Properties of DASPMI as Revealed by Spectrally Resolved Fluorescence Decays
Ramadass R and Bereiter-Han J
The Journal of Physical Chemistry B, 111 (26), 7681?7690-7681?7690 (2007)
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