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Merck
CN

280135

Sigma-Aldrich

2-[4-(二甲氨基)苯乙烯基]-1-甲基吡啶碘

Dye content 95 %

别名:

2-Di-1-ASP

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关于此项目

经验公式（希尔记法）:
C16H19IN2
CAS Number:
2156-29-8
分子量:
366.24
Beilstein:
3776369
EC 号:
218-460-8
MDL编号:
MFCD00011980
UNSPSC代码:
12352103
PubChem化学物质编号:
57648287
NACRES:
NA.23

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表单

solid

组成

Dye content, 95%

mp

280 °C (dec.) (lit.)

λmax

466 nm

荧光

λex 466 nm; λem 504 nm in methanol
λex 475 nm; λem 589 nm in methanol

SMILES字符串

[I-].CN(C)c1ccc(cc1)\C=C\c2cccc[n+]2C

InChI

1S/C16H19N2.HI/c1-17(2)15-10-7-14(8-11-15)9-12-16-6-4-5-13-18(16)3;/h4-13H,1-3H3;1H/q+1;/p-1

InChI key

XPOIQAIBZGSIDD-UHFFFAOYSA-M

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一般描述

2-[4-（二甲基氨基）苯乙烯基]-1-甲基碘化吡啶（DASPMI）是一种线粒体染色苯乙烯基染料，用于通过施加跨膜电位的变化来产生快速响应机制。DASPMI可以用作低毒性染色剂，显示线粒体的荧光行为。

应用

DASPMI广泛用于活细胞中线粒体的选择性染色。
DASPMI是一种极性敏感染料，可测量活细胞中线粒体的膜电位。它可以在基于光引发剂的系统的开发中用作光吸收剂。

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H315,H319,H335

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCL8555
MKBR0101V
04305MX
11620DD

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Distribution pattern of viable mitochondria in bovine lens epithelial cells.
O Leip et al.
Developments in ophthalmology, 26, 90-96 (1994-01-01)
Microtubules mediate mitochondrial distribution in fission yeast
Yaffe MP, et al.
Proceedings of the National Academy of Sciences of the USA, 93, 11664-11668 (1996)
Use of fluorescent probes to investigate the metabolic state of Pneumocystis carinii mitochondria.
F Chen et al.
The Journal of eukaryotic microbiology, 41(5), 79S-79S (1994-09-01)
J W Li et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 29(4), 316-319 (1994-01-01)
A reversed phase high performance liquid chromatography (RP-HPLC) method for determination of 2-(p-dimethylaminostyryl) pyridine methiodide (DSPM) concentration in rabbit plasma is reported. The stationary phase was YWG-C18H37. The mobile phase consisted of 80% CH3OH, 20% CH3COOH-CH3COONa buffer (pH 4.0, 0.20
Dibakar Sahoo et al.
The journal of physical chemistry. B, 114(5), 2044-2050 (2010-01-22)
The mode of binding of 2-(4-(dimethylamino)styryl)-1-methylpyridinium iodide (DASPMI) with calf thymus DNA as revealed from different steady state and time-resolved emission spectroscopic measurements has been reported in this paper. Fluorescence enhancement of DASPMI and its quenching by potassium iodide (KI)
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