280550
双苯比拉林 盐酸盐
95%
别名:
4-二苯甲氧基-1-甲基哌啶, 二苯拉林 盐酸盐
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关于此项目
经验公式（希尔记法）:
C19H23NO · HCl
化学文摘社编号:
分子量:
317.85
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
205-049-3
MDL number:
Assay:
95%
Quality Level
assay
95%
mp
203-205 °C (lit.)
functional group
ether, phenyl
SMILES string
Cl[H].CN1CCC(CC1)OC(c2ccccc2)c3ccccc3
InChI
1S/C19H23NO.ClH/c1-20-14-12-18(13-15-20)21-19(16-8-4-2-5-9-16)17-10-6-3-7-11-17;/h2-11,18-19H,12-15H2,1H3;1H
InChI key
LPRLDRXGWKXRMQ-UHFFFAOYSA-N
Gene Information
human ... HRH1(3269)
General description
4-Diphenylmethoxy-1-methylpiperidine hydrochloride is also referred as diphenylpyraline hydrochloride (DPP), is a first-generation antihistamine.
Application
4-Diphenylmethoxy-1-methylpiperidine hydrochloride was used as a pharmacotherapy for Parkinson′s disease.
T Ohno et al.
Journal of the neurological sciences, 182(2), 95-97 (2001-01-04)
A long-term follow-up study was made of three patients with cerebrotendinous xanthomatosis (CTX) associated with parkinsonism, two of whom were siblings. Besides typical CTX symptoms, all three patients showed severe parkinsonism. This observation has been rarely reported in CTX. The
N Shibata et al.
Rinsho shinkeigaku = Clinical neurology, 30(9), 978-984 (1990-09-01)
Two sibling cases of cerebrotendinous xanthomatosis with parkinsonism were reported. One was a woman of 39 years old, and another was her sister of 36 years old. In both cases, febrile convulsion appeared on 1.5 year old, and mental deterioration
Chika Hasegawa et al.
Rapid communications in mass spectrometry : RCM, 20(4), 537-543 (2006-01-19)
Ten antihistamine drugs, diphenhydramine, orphenadrine, chlorpheniramine, diphenylpyraline, triprolidine, promethazine, homochlorcyclizine, cyproheptadine, cloperastine and clemastine, have been found to be extractable from human plasma samples using MonoTip C18 tips, inside which C18- bonded monolithic silica gel was fixed. Human plasma (0.1
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 280550-10G | 04061833045626 |