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Merck
CN

282227

洗必泰

≥99.5%

别名:

1,1′-己基双[5-(对氯苯基)双胍]

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关于此项目

线性分子式:
[-(CH2)3NHC(=NH)NHC(=NH)NHC6H4Cl]2
化学文摘社编号:
分子量:
505.45
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
200-238-7
Beilstein/REAXYS Number:
2826432
MDL number:
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产品名称

洗必泰, ≥99.5%

InChI key

GHXZTYHSJHQHIJ-UHFFFAOYSA-N

InChI

1S/C22H30Cl2N10/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34)

SMILES string

Clc1ccc(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(Cl)cc2)cc1

assay

≥99.5%

form

powder

impurities

<1.0% water

mp

134-136 °C (lit.)

solubility

water: soluble 0.08% at 20 °C

functional group

amine
chloro

Quality Level

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Application

氯己定是口服防腐剂的“金标准”,已被用于优化外科缝线中基于脂肪酸的新型缓释氯己定涂层。。氯己定,一种抗菌剂,已被用于制备氯己定功能化的磷酸钙纳米粒子,其可用于口腔卫生和牙科治疗领域

General description

已对氯己定:羟丙基-β-环糊精包含物对牛牙本质体外平板的影响进行了研究

氯己定是一种阳离子表面活性剂,具有广谱抗微生物活性。它用作牙周治疗和手术刷洗中的消毒剂。

pictograms

CorrosionEnvironment

signalword

Danger

hcodes

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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分析证书(COA)

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Chlorhexidine-loaded calcium phosphate nanoparticles for dental maintenance treatment: combination of mineralising and antibacterial effects.
Kovtun A, et al.
Royal Society of Chemistry Advances, 2(3), 870-875 (2012)
Effect of a chlorhexidine mouthrinse on plaque, gingival inflammation and staining in gingivitis patients: a systematic review
Van Strydonck DA, et al.
Journal of Clinical Periodontology, 39, 1042-1055 (2012)
Carolina Ferreira Franco et al.
Artificial organs, 27(5), 486-491 (2003-05-20)
The aim of this work was study the effect of the chlorhexidine : hydroxypropyl-beta-cyclodextrin (CLX : HP-beta-CD) inclusion compound (IC) on in vitro slabs of bovine dentine. The substantivity, antimicrobial activity, and morphological effect of this inclusion compound were evaluated.
Carolyne Horner et al.
The Journal of antimicrobial chemotherapy, 67(11), 2547-2559 (2012-07-27)
Antiseptic agents are increasingly used for hand hygiene and skin decolonization as key tools for the prevention of healthcare-associated infections. Chlorhexidine, a divalent, cationic biguanide, has a broad spectrum of activity and is one of the most frequently used topical
S Karki et al.
The Journal of hospital infection, 82(2), 71-84 (2012-08-15)
The topical use of chlorhexidine gluconate (CHG) is intended to reduce bacterial density on patients' skin. To assess the impact of body bath or skin cleansing with CHG-impregnated or CHG-saturated washcloths in preventing healthcare-associated infections and colonization. This systematic review

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