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Merck
CN

282227

洗必泰

≥99.5%

别名:

1,1′-己基双[5-(对氯苯基)双胍]

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关于此项目

线性分子式:
[-(CH2)3NHC(=NH)NHC(=NH)NHC6H4Cl]2
化学文摘社编号:
分子量:
505.45
Beilstein:
2826432
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
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方案

≥99.5%

表单

powder

杂质

<1.0% water

mp

134-136 °C (lit.)

溶解性

water: soluble 0.08% at 20 °C

官能团

amine
chloro

SMILES字符串

Clc1ccc(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(Cl)cc2)cc1

InChI

1S/C22H30Cl2N10/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34)

InChI key

GHXZTYHSJHQHIJ-UHFFFAOYSA-N

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一般描述

已对氯己定:羟丙基-β-环糊精包含物对牛牙本质体外平板的影响进行了研究

氯己定是一种阳离子表面活性剂,具有广谱抗微生物活性。它用作牙周治疗和手术刷洗中的消毒剂。

应用

氯己定是口服防腐剂的“金标准”,已被用于优化外科缝线中基于脂肪酸的新型缓释氯己定涂层。。氯己定,一种抗菌剂,已被用于制备氯己定功能化的磷酸钙纳米粒子,其可用于口腔卫生和牙科治疗领域

象形图

CorrosionEnvironment

警示用语:

Danger

危险声明

危险分类

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Carolina Ferreira Franco et al.
Artificial organs, 27(5), 486-491 (2003-05-20)
The aim of this work was study the effect of the chlorhexidine : hydroxypropyl-beta-cyclodextrin (CLX : HP-beta-CD) inclusion compound (IC) on in vitro slabs of bovine dentine. The substantivity, antimicrobial activity, and morphological effect of this inclusion compound were evaluated.
Effect of a chlorhexidine mouthrinse on plaque, gingival inflammation and staining in gingivitis patients: a systematic review
Van Strydonck DA, et al.
Journal of Clinical Periodontology, 39, 1042-1055 (2012)
Chlorhexidine-loaded calcium phosphate nanoparticles for dental maintenance treatment: combination of mineralising and antibacterial effects.
Kovtun A, et al.
Royal Society of Chemistry Advances, 2(3), 870-875 (2012)
Steven P Engebretson et al.
JAMA, 310(23), 2523-2532 (2013-12-19)
Chronic periodontitis, a destructive inflammatory disorder of the supporting structures of the teeth, is prevalent in patients with diabetes. Limited evidence suggests that periodontal therapy may improve glycemic control. To determine if nonsurgical periodontal treatment reduces levels of glycated hemoglobin
S Karki et al.
The Journal of hospital infection, 82(2), 71-84 (2012-08-15)
The topical use of chlorhexidine gluconate (CHG) is intended to reduce bacterial density on patients' skin. To assess the impact of body bath or skin cleansing with CHG-impregnated or CHG-saturated washcloths in preventing healthcare-associated infections and colonization. This systematic review

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