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284297

2-巯基咪唑

Name: 2-巯基咪唑
Brand: ALDRICH

98%

别名:

2-咪唑硫醇

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关于此项目

经验公式（希尔记法）:

C₃H₄N₂S

化学文摘社编号:

872-35-5

分子量:

100.14

UNSPSC Code:

12352005

NACRES:

NA.22

PubChem Substance ID:

24857146

EC Number:

212-823-4

Beilstein/REAXYS Number:

105775

MDL number:

MFCD00005188

Assay:

98%

Form:

solid

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属性

Quality Level

100

assay

98%

form

solid

mp

228-231 °C (lit.)

solubility

methanol: soluble 50 mg/mL, clear to slightly hazy, colorless to yellow

SMILES string

Sc1ncc[nH]1

InChI

1S/C3H4N2S/c6-3-4-1-2-5-3/h1-2H,(H2,4,5,6)

InChI key

OXFSTTJBVAAALW-UHFFFAOYSA-N

说明

General description

2-巯基咪唑对蘑菇酪氨酸酶的抑制动力学已得到研究。对于在生物学和工业上具有重要意义的2-巯基咪唑，以通过pH依赖性的表面增强拉曼散射（SERS）光谱对其在1.0×10^-10M的浓度下进行了研究。

Application

2-巯基咪唑已被用于硅胶的化学改性，用于从水相溶液中选择性分离汞（II）。

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Regulation of thyroid sodium-iodide symporter in different stages of goiter: Possible involvement of reactive oxygen species.

Lívia P L Matos et al.

Clinical and experimental pharmacology & physiology, 45(4), 326-334 (2017-11-08)

Na+ /I- symporter (NIS) transports iodide into thyrocytes, a fundamental step for thyroid hormone biosynthesis. Our aim was to evaluate NIS regulation in different status of goitrogenesis and its underlying mechanisms. Wistar rats were treated with methimazole (MMI) for 5

Inhibitory effects of novel synthetic methimazole derivatives on mushroom tyrosinase and melanogenesis.

Chin-Feng Chan et al.

Bioorganic & medicinal chemistry, 22(9), 2809-2815 (2014-04-08)

In this study, we synthesized 4 methimazole (2-mercapto-1-methylimidazole, MMI) derivatives. The kinetics of inhibition on mushroom tyrosinase by methimazole and its derivatives were investigated. The results indicated that tert-butyl 3-methyl-2-sulfanylidene-2,3-dihydro-1H-imidazole-1-carboxylate (compound 3; 3), 2-mercaptoimidazole (MI; compound 1; 1) and MMI

Exploring the pH dependent SERS spectra of 2-mercaptoimidazole molecule adsorbed on silver nanocolloids in the light of Albrecht's "A" term and Herzberg-Teller charge transfer contribution.

Subhendu Chandra et al.

Journal of colloid and interface science, 399, 33-45 (2013-04-02)

The pH dependent surface-enhanced Raman scattering (SERS) spectra of biologically and industrially significant, 2-mercaptoimidazole (2-MI) molecule at 1.0×10(-10)M concentration have been investigated. The pH dependent SERS spectra are compared with the corresponding normal Raman spectra (NRS) of the molecule. The

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全球贸易项目编号

货号	GTIN
284297-5G	04061826253366
284297-1G	04061826253359